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Memantine hydrochloride

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Identification
Molecular formula
C12H22ClN
CAS number
41100-52-1
IUPAC name
N-methyladamantan-2-amine;hydrochloride
State
State

Memantine hydrochloride is typically in a solid state at room temperature. As a pharmaceutical compound, it is often formulated into tablets or capsules for oral administration.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
215.77g/mol
Molar mass
215.7650g/mol
Density
1.2000g/cm3
Appearence

Memantine hydrochloride appears as a white to off-white crystalline powder. It is hygroscopic, which means it can absorb moisture from the air. It is usually provided in a solid form, suitable for use in pharmaceuticals.

Comment on solubility

Solubility of N-methyladamantan-2-amine;hydrochloride

N-methyladamantan-2-amine;hydrochloride, often referred to as a salt form of an amine compound, exhibits particular solubility characteristics that are noteworthy. Its solubility is influenced by several factors:

  • Polarity: Being a quaternary ammonium salt, it tends to be more soluble in polar solvents such as water due to the presence of the hydrochloride moiety.
  • Temperature: The solubility generally increases with an increase in temperature, allowing for greater dissolution in solution.
  • pH Influence: As a hydrochloride salt, it is more soluble in acidic environments compared to neutral or basic conditions, where it may precipitate.

In practical terms, one might say, "Solubility opens the door to accessibility," emphasizing how understanding the solubility behavior of N-methyladamantan-2-amine;hydrochloride can facilitate its use in various applications, from pharmaceuticals to chemical research. When preparing solutions, it is essential to consider these factors to achieve desired concentrations efficiently.

In summary, N-methyladamantan-2-amine;hydrochloride is reasonably soluble in water, particularly influenced by temperature and pH, making it a useful compound in contexts where solvation plays a critical role.

Interesting facts

N-methyladamantan-2-amine; hydrochloride

N-methyladamantan-2-amine; hydrochloride, often referred to as a derivative of adamantane, presents a fascinating area of study in medicinal chemistry. As a compound, it combines the structural rigidity of the adamantane framework with the functionality of an amine group, offering unique properties and potential applications.

Key Characteristics:

  • Structure: The adamantane core consists of a fused diamond-like cage structure that contributes to the compound's stability and hydrophobic nature.
  • Pharmacological Potential: The amine functional group is critical for interaction with biological targets, making this compound a candidate for research in drug development and neuropharmacology.
  • CNS Activity: Research indicates that compounds with similar structures may exhibit central nervous system (CNS) activity, positioning N-methyladamantan-2-amine; hydrochloride as a potential candidate for studying neuroactive functions.

Moreover, its synthesis presents intriguing challenges and opportunities for chemists, often involving methods such as:

  1. Direct alkylation of adamantane derivatives.
  2. Reduction reactions that help fine-tune the compound's properties.

In summary, N-methyladamantan-2-amine; hydrochloride serves as a vital subject for exploration in various chemistry domains, especially in the realms of drug discovery and medicinal chemistry, showcasing how small modifications to molecular structures can lead to significant functional differences. As researchers continue to delve into its potential, the impact of this compound could be profound in therapeutic applications.

Synonyms
N-methyladamantan-2-amine hydrochloride
963-708-7
10523-69-0
N-methyl-2-adamantanamine hydrochloride
2-ADAMANTANAMINE, N-METHYL-, HYDROCHLORIDE
N-methyladamantan-2-amine;hydrochloride
N-Methyl-2-adamantanaminehydrochloride
2-(N-Methylamine)adamantane hydrochloride
Tricyclo(3.3.1.1(sup 3,7))decan-2-amine, N-methyl-, hydrochloride
SCHEMBL28783872
DTXSID20147022
KAA52369
AKOS026744066
CS-0245628
EN300-30759
Z317046600