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N-Methylbenzamide

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Identification
Molecular formula
C8H9NO
CAS number
613-93-4
IUPAC name
N-methylbenzamide
State
State

N-Methylbenzamide is typically in a solid state at room temperature.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
292.20
Boiling point (Kelvin)
565.35
General information
Molecular weight
135.17g/mol
Molar mass
135.1650g/mol
Density
1.0804g/cm3
Appearence

N-Methylbenzamide is a white crystalline solid. It may appear as powdery or flaky particles and is generally colorless in its pure form. This compound has no significant odor and is often utilized in organic synthesis processes.

Comment on solubility

Solubility of N-methylbenzamide

N-methylbenzamide, with the chemical formula C8H9NO, exhibits interesting solubility characteristics that are important for its applications in various chemical processes.

In general, the solubility of N-methylbenzamide can be understood through the following key points:

  • Polarity: N-methylbenzamide is a polar compound due to the presence of the amide functional group, which facilitates interactions with polar solvents.
  • Solvent Compatibility: It is soluble in common polar solvents such as:
    • Water
    • Methanol
    • Ethanol
  • Hydrophobic Characteristics: While it is soluble in polar solvents, N-methylbenzamide has lesser solubility in nonpolar solvents such as hexane or benzene, owing to its hydrophobic aromatic ring structure.

"Like dissolves like" is a handy phrase that captures the essence of solubility behavior, emphasizing that polar and nonpolar solvents will not dissolve each other effectively.

This solubility profile makes N-methylbenzamide a versatile compound in organic synthesis and pharmaceuticals, as its solubility in polar solvents can aid in reactions and purification processes.

Interesting facts

N-methylbenzamide: A Closer Look

N-methylbenzamide, a fascinating compound in the realm of amides, boasts a variety of intriguing features that appeal to both chemists and enthusiasts alike. Here are some noteworthy aspects:

  • Functional Group: As an amide, N-methylbenzamide contains a carbonyl group (C=O) adjacent to a nitrogen atom. This structure plays a vital role in its chemical reactivity and overall properties.
  • Applications: This compound is widely used in the synthesis of pharmaceuticals and agrochemicals. Its ability to act as a building block in various organic transformations makes it highly valuable in medicinal chemistry.
  • Solvation and Hydrogen Bonding: The presence of both the nitrogen atom and the carbonyl group allows for the possibility of hydrogen bonding. This property is crucial as it can influence the compound's behavior in different solvent systems.
  • Toxicological Considerations: While many compounds can exhibit toxicity, studies on N-methylbenzamide indicate that it is relatively safe at typical exposure levels. However, proper handling and safety measures are always recommended when dealing with chemical compounds.
  • Analytical Techniques: Scientists often utilize methods such as NMR spectroscopy and mass spectrometry to characterize N-methylbenzamide. These techniques provide detailed insights into its molecular structure and dynamics.

In the words of chemist Robert H. Grubbs, "Chemistry is a central science, bridging the physical sciences with the life sciences and applied sciences." N-methylbenzamide exemplifies this bridge, showcasing the importance of studying both organic and inorganic interactions in chemistry.

As you delve deeper into N-methylbenzamide and its potential, remember that the compound not only exemplifies core chemical principles but also opens doors for innovations in research and technology.

Synonyms
N-METHYLBENZAMIDE
Benzamide, N-methyl-
N-Methylbenzenamide
N-Methylbenzenecarboxamide
CCRIS 4670
EINECS 210-362-3
NSC 42944
UNII-K3ED781E08
BRN 1209880
DTXSID5025570
AI3-01069
K3ED781E08
NSC-42944
METHYLBENZAMIDE, N-
DTXCID605570
NCCHARWOCKOHIH-UHFFFAOYSA-
4-09-00-00727 (Beilstein Handbook Reference)
NMethylbenzenamide
Benzamide, Nmethyl
NMethylbenzenecarboxamide
210-362-3
inchi=1/c8h9no/c1-9-8(10)7-5-3-2-4-6-7/h2-6h,1h3,(h,9,10)
nccharwockohih-uhfffaoysa-n
613-93-4
N-Methyl-benzamide
MFCD00011642
N-methyl benzamide
N-METHYLBENZENEAMIDE
WLN: 1MVR
SCHEMBL6100
N-Methylbenzamide, >=99%
CHEMBL275261
SCHEMBL7551593
SCHEMBL9580804
AAA61393
NSC42944
Tox21_200220
AKOS002304094
NCGC00091232-01
NCGC00091232-02
NCGC00257774-01
AS-11419
CAS-613-93-4
SY037937
DB-053865
HY-135848
CS-0114596
NS00021249
EN300-131692
F16588
AP-065/40250235
Q27281901
Z32016410