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Metformin hydrochloride

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Identification
Molecular formula
C4H12N5Cl
CAS number
1115-70-4
IUPAC name
[N'-[N'-(3-chlorophenyl)carbamimidoyl]carbamimidoyl]ammonium;chloride
State
State

At room temperature, Metformin hydrochloride is typically found as a crystalline solid.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
201.80
Boiling point (Kelvin)
474.95
General information
Molecular weight
165.63g/mol
Molar mass
165.6250g/mol
Density
1.5000g/cm3
Appearence

Metformin hydrochloride appears as a white to off-white crystalline powder. It is odorless or almost odorless, and hygroscopic. The compound is freely soluble in water and slightly soluble in ethanol.

Comment on solubility

Solubility of N'-[N'-(3-chlorophenyl)carbamimidoyl]carbamimidoyl]ammonium; chloride

The solubility of the compound N'-[N'-(3-chlorophenyl)carbamimidoyl]carbamimidoyl]ammonium; chloride can be influenced by a variety of factors, including temperature, pH, and the presence of solvents.

General Considerations

Typically, ammonium salts like this one demonstrate the following characteristics in terms of solubility:

  • Water Solubility: Many ammonium salts are highly soluble in water, and the presence of the chloride ion further promotes solubility.
  • Temperature Dependency: Solubility can increase with rising temperatures; higher temperatures often break solute-solvent interactions.
  • Interaction with Solvents: In polar solvents, such as water, solubility is usually considerable due to strong solvation.

Factors Affecting Solubility

When considering the solubility of the compound, it is essential to take into account:

  • The ionization of the compound in solution.
  • Potential interactions with specific ions or molecules in the solvent.
  • The molecular structure and substituents, such as the 3-chlorophenyl group, which can influence solubility through sterics and electronics.

In laboratory conditions, it is advisable to conduct solubility tests at varying pH levels and temperatures to achieve a comprehensive understanding of this compound's solubility profile.

Interesting facts

Interesting Facts about N'-[N'-(3-chlorophenyl)carbamimidoyl]carbamimidoyl]ammonium;chloride

N'-[N'-(3-chlorophenyl)carbamimidoyl]carbamimidoyl]ammonium;chloride is a fascinating compound that belongs to the class of guanidine derivatives, which have garnered significant attention in the realm of medicinal chemistry.

Here are some engaging facts about this intriguing compound:

  • Pharmacological Significance: Guanidine derivatives are known for their diverse pharmacological properties, including antibacterial, antifungal, and anticancer effects, making this compound a subject of interest for drug development.
  • Mechanism of Action: Compounds like this can act as enzyme inhibitors or modulators, illustrating the importance of structural variations in influencing biological activity. The presence of the 3-chlorophenyl group may enhance its biological interactions.
  • Research Applications: This compound has potential applications in biochemical research, particularly in studies exploring nitrogen metabolism and the role of guanidine in cellular processes.
  • Structural Complexity: The intricate structure of N'-[N'-(3-chlorophenyl)carbamimidoyl]carbamimidoyl]ammonium;chloride showcases the fascinating chemistry of carbamimidoyl functional groups, which contribute to its unique properties.

As a chemist, it is always exhilarating to explore compounds such as this and uncover their potential roles in health and disease. Each compound holds a story that weaves through its chemical structure, biological activity, and practical applications, and N'-[N'-(3-chlorophenyl)carbamimidoyl]carbamimidoyl]ammonium;chloride is no exception. This compound invites further research and curiosity, driving scientists to delve deeper into its possible uses in modern medicine.