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N-(o-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

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Identification
Molecular formula
C18H21N3O2
CAS number
29136-03-8
IUPAC name
N-(o-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide
State
State

At room temperature, this compound exists in a solid state, typically in the form of a powder or crystalline solid.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
515.30
Boiling point (Kelvin)
788.45
General information
Molecular weight
313.40g/mol
Molar mass
313.3960g/mol
Density
1.2700g/cm3
Appearence

N-(o-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide typically appears as a solid compound. The solid form may have a crystalline texture, often appearing as a powder or fine granules. The color can vary depending on the purity and sample preparation but generally ranges from off-white to light yellow.

Comment on solubility

Solubility of N-(o-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

N-(o-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide, due to its complex structure, exhibits a nuanced solubility profile in various solvents. Understanding its solubility can help predict its behavior in different chemical environments.

Key Points About Solubility:

  • Polar vs. Non-Polar Solvents: This compound likely shows better solubility in polar solvents, such as water or methanol, due to the presence of polar functional groups.
  • Hydrogen Bonding: The presence of amide and hydrazine groups can facilitate hydrogen bonding, which can enhance solubility in polar media.
  • Influence of the Aromatic Rings: The aromatic o-tolyl and pyridine rings can contribute to hydrophobic characteristics, potentially decreasing solubility in more non-polar solvents.
  • Temperature Dependency: Solubility may increase with temperature, a common characteristic of many organic compounds.

As a general rule of thumb, “like dissolves like,” and the unique balance of hydrophilic and hydrophobic regions in N-(o-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide impacts its solubility in various solvents significantly. Understanding these characteristics can aid in its application and usage in chemical processes.

Interesting facts

Interesting Facts about N-(o-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

N-(o-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide is a fascinating compound with unique properties and applications. Here are some engaging aspects of this chemical:

  • Structural Complexity: This compound features a multi-functional structure, which includes an o-tolylmethyl group and a pyridine moiety, known for its aromatic and electron-deficient characteristics.
  • Biological Relevance: Compounds like this often play critical roles in medicinal chemistry, potentially serving as novel drug candidates due to their ability to interact with biological systems. Researchers constantly explore derivatives for their therapeutic efficacy.
  • Synthetic Pathways: The synthesis of hydrazones and amides showcases the versatility of organic reactions in creating complex molecules. Understanding these pathways is essential for chemists looking to design similar compounds.
  • Research Applications: Due to the presence of a hydrazino functional group, compounds like N-(o-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide are investigated for their potential antioxidant and anti-inflammatory properties.

As scientists delve into the properties of this compound, they are not just interested in its chemical structure but also in the possibilities it opens for research in areas such as drug discovery and materials science. In the words of a prominent chemist, "Understanding small complexes can often lead us to significant breakthroughs in larger systems."

Overall, N-(o-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide exemplifies the interplay between organic synthesis and biological functionality, making it a compelling subject for further exploration.

Synonyms
P 1250
BRN 0492747
ISONICOTINIC ACID, 2-(2-((o-METHYLBENZYL)CARBAMOYL)ETHYL)HYDRAZIDE
15806-15-2
DTXSID30166360
DTXCID3088851