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N'-(p-tolyl)pyridine-4-carboxamidine

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Identification
Molecular formula
C13H13N3
CAS number
463921-06-2
IUPAC name
N'-(p-tolyl)pyridine-4-carboxamidine
State
State

At room temperature, the compound is in a solid state, typically described as a crystalline powder.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
211.27g/mol
Molar mass
211.2700g/mol
Density
1.2100g/cm3
Appearence

The compound typically appears as a crystalline powder or solid. The color can vary but is often off-white to pale yellow.

Comment on solubility

Solubility of N'-(p-tolyl)pyridine-4-carboxamidine

N'-(p-tolyl)pyridine-4-carboxamidine, a fascinating organic compound, exhibits a range of solubility characteristics that are important to its applications in various fields. The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of the pyridine moiety gives it some polar characteristics, which can enhance solubility in polar solvents.
  • Organic Solvents: N'-(p-tolyl)pyridine-4-carboxamidine is expected to have greater solubility in non-polar to moderately polar organic solvents such as ethanol, methanol, or acetonitrile.
  • Water Solubility: Due to its relatively hydrophobic structure, the solubility in water might be limited, making it more soluble in organic media.

Understanding the solubility of this compound is essential for its application in various chemical reactions and formulations. For instance, it can be said that:

“The solubility of a compound is a key factor that governs its reactivity and usability in synthesis.”

In summary, while N'-(p-tolyl)pyridine-4-carboxamidine may not be highly soluble in aqueous solutions, it finds better solubility profiles in appropriate organic solvents which can facilitate its use in various chemical processes.

Interesting facts

Interesting Facts about N'-(p-tolyl)pyridine-4-carboxamidine

N'-(p-tolyl)pyridine-4-carboxamidine, often abbreviated as p-Tol-PCA, is a fascinating compound that belongs to the family of amidines. This compound plays a significant role in various fields of chemistry and biological research. Here are some intriguing aspects surrounding this compound:

  • Biological Significance: Research indicates that amidines, such as p-Tol-PCA, can have noteworthy pharmacological properties. They are often studied for their potential use in developing antiviral, anti-inflammatory, and antitumor agents.
  • Structural Features: The presence of a pyridine ring in its structure makes this compound particularly interesting. The aromatic nature of pyridine contributes to its stability and reactivity, making it a versatile building block in synthetic chemistry.
  • Research Tool: Because of its unique chemical properties, p-Tol-PCA is utilized in various research applications, enabling scientists to probe biological mechanisms at the molecular level.
  • Potential in Materials Science: The derivatives of this compound have sparked interest in the development of novel materials and polymers with tailored properties by modifying their chemical structure.
  • Chiral Connectivity: The chiral environment around the amidine moiety could lead to enantiomeric forms of the compound, which may exhibit different biological activities, opening doors for chiral drug development.

In summary, N'-(p-tolyl)pyridine-4-carboxamidine is more than just a chemical compound; it represents a junction of organic chemistry, pharmacology, and materials science, illustrating the profound impact that even a single molecule can have on scientific advancement and discovery.

Synonyms
N-p-Tolylisonicotinamidine
ISONICOTINAMIDINE, N-p-TOLYL-
BRN 0475594
23564-34-3
4-Pyridinecarboximidamide, N-(4-methylphenyl)-
DTXSID70178164
RefChem:349664
DTXCID00100655
SCHEMBL4861779
SCHEMBL4861785
ANXBBENPWKWPST-UHFFFAOYSA-N
N-(4-Methylphenyl)pyridine-4-carboximidamide