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N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide

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Identification
Molecular formula
C13H13N3O3S
CAS number
181024-58-0
IUPAC name
N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide
State
State

At room temperature, N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide is typically a solid.

Melting point (Celsius)
181.00
Melting point (Kelvin)
454.15
Boiling point (Celsius)
448.70
Boiling point (Kelvin)
721.85
General information
Molecular weight
301.33g/mol
Molar mass
301.3340g/mol
Density
1.2900g/cm3
Appearence

N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide generally appears as a crystalline solid. It is characterized by its white to off-white color. Being a complex organic compound, its appearance might vary slightly depending on the purity and specific form it takes.

Comment on solubility

Solubility of N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide

N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide is a compound with specific solubility characteristics that are worth exploring. Understanding the solubility of this compound is crucial for its applications in various chemical processes.

Solubility Characteristics:

  • Solvent Compatibility: This compound is mostly soluble in polar organic solvents such as DMSO (dimethyl sulfoxide) and DMF (dimethylformamide). This indicates a strong interaction with polar solvents.
  • Water Solubility: On the other hand, its solubility in water is significantly limited, which is common for many organic compounds due to hydrophobic interactions.
  • Temperature Effects: Like many chemical compounds, solubility may increase with temperature, making the compound more dissolvable in heated solvents.

The polar nature of N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide contributes to its ability to dissolve in certain organic solvents, while its structural composition limits its interaction with water. In summary, understanding the solubility profile of this compound is essential for its effective use in synthetic chemistry and pharmaceutical applications.

Interesting facts

Interesting Facts about N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide

N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide is a fascinating compound that belongs to the category of hydrazides and is often utilized in various fields of chemistry, especially in medicinal chemistry and synthetic organic chemistry. Here are some interesting aspects to consider:

  • Pharmacological Potential: This compound exhibits remarkable biological activities, making it a compound of interest in the development of new pharmaceuticals. Studies have shown that it may possess antimicrobial and anticancer properties.
  • Versatile Applications: Beyond its potential in drug discovery, N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide can also be used as a building block in organic synthesis, contributing to the creation of more complex molecules.
  • Structural Characteristics: The sulfonyl group attached to the pyridine ring enhances both the stability and reactivity of this compound, allowing for various chemical transformations that are essential in synthetic pathways.
  • Research Importance: Scientists are continuously exploring this compound to better understand its mechanism of action and potential therapeutic effects. As research progresses, it could lead to significant advancements in treating various diseases.
  • Educational Use: Being a sophisticated compound, it serves as an excellent example in advanced organic chemistry courses, illustrating concepts such as reactivity and functional group transformations.

In summary, N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide is not just a chemical substance; it represents a converging point of chemistry, pharmacology, and innovative research. It embodies the creativity and complexity involved in the synthesis and application of chemical compounds, making it a subject of great interest for both students and professionals alike.

Synonyms
6281-93-2
NICOTINIC ACID, 2-((p-TOLYL)SULFONYL)HYDRAZIDE
Nicotinic acid, p-tolylsulfonylhydrazide
NSC 5933
AUF1I4P99D
NSC 50553
BRN 0425296
Nicotinic p-tolylsulfonylhydrazide
NSC-5933
NSC-50553
UNII-AUF1I4P99D
3-Pyridinecarboxylic acid, 2-((4-methylphenyl)sulfonyl)hydrazide
DTXSID50211922
N(sub 1)-Nicotinoyl-N(sub 2)-p-tolyl-sulfonhydrazine [French]
N(sub 1)-Nicotinoyl-N(sub 2)-p-tolyl-sulfonhydrazine
DTXCID80134413
3-Pyridinecarboxylic acid, 2-((4-methylphenyl)sulfonyl)hydrazide (9CI)
N'-(4-methylphenyl)sulfonylpyridine-3-carbohydrazide
N'-(p-tolylsulfonyl)pyridine-3-carbohydrazide
CBDivE_009059
MLS000685476
SCHEMBL6226011
CHEMBL1311428
NSC5933
HMS2587A15
NSC50553
STL482162
AKOS001612996
NCGC00245838-01
SMR000312440
SR-01000404280
SR-01000404280-1
N'-[(4-methylphenyl)sulfonyl]pyridine-3-carbohydrazide
N'1-(3-pyridylcarbonyl)-4-methylbenzene-1-sulfonohydrazide
N'-(4-METHYLBENZENESULFONYL)PYRIDINE-3-CARBOHYDRAZIDE