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Phencyclidine hydrochloride

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Identification
Molecular formula
C17H24ClN2O
CAS number
956-90-1
IUPAC name
N-[phenyl-(1-piperidin-1-ium-1-ylcyclohexyl)methylene]acetamide;chloride
State
State

At room temperature, phencyclidine hydrochloride is a solid. It is commonly encountered in its salt form as a crystalline powder or granular solid.

Melting point (Celsius)
229.00
Melting point (Kelvin)
502.15
Boiling point (Celsius)
153.20
Boiling point (Kelvin)
426.35
General information
Molecular weight
304.89g/mol
Molar mass
304.8850g/mol
Density
1.0139g/cm3
Appearence

Phencyclidine hydrochloride typically appears as a crystalline powder. Its appearance can vary slightly but usually presents as a clear, white solid that may take the form of small crystals or powder.

Comment on solubility

Solubility of N-[phenyl-(1-piperidin-1-ium-1-ylcyclohexyl)methylene]acetamide;chloride

The solubility of N-[phenyl-(1-piperidin-1-ium-1-ylcyclohexyl)methylene]acetamide;chloride in various solvents can provide valuable insights into its chemical behavior and potential applications. Here are a few key points regarding its solubility:

  • Polar Solvents: Typically, compounds with ionic or charged groups tend to be soluble in polar solvents such as water or methanol. Given that this compound contains a piperidine ring which can carry a positive charge, it may exhibit some degree of solubility in polar solvents.
  • Non-Polar Solvents: Conversely, solubility in non-polar solvents (like hexane) is generally low for such compounds due to the lack of favorable interactions with these solvents.
  • pH Sensitivity: The solubility of this compound may also be affected by the pH of the solution, as it contains amide functionalities which can engage in protonation or deprotonation reactions.
  • Temperature Effects: As with many chemical compounds, solubility can increase with temperature. Thus, higher temperatures may help improve the solubility of this compound in various solvents.

Overall, the solubility characteristics of N-[phenyl-(1-piperidin-1-ium-1-ylcyclohexyl)methylene]acetamide;chloride may vary significantly depending on the solvent type and conditions, making it crucial to conduct empirical studies to determine its precise solubility profile.

Interesting facts

Interesting Facts about N-[Phenyl-(1-piperidin-1-ium-1-ylcyclohexyl)methylene]acetamide; Chloride

This compound, a derivative of acetamide, falls into the category of complex organic molecules, holding significance in both medicinal chemistry and material sciences. Its intricate structure encompasses the following features:

  • Piperidine Moiety: The presence of the piperidin-1-ium unit offers this compound unique behavioral characteristics, often influencing its pharmacological profile.
  • Phenyl Group: The phenyl component enhances the compound’s potential for interaction with various biological targets, making it a candidate for drug development and investigation.
  • Application Potential: Due to its unique structure, it has been studied for its effects in neurological studies, possibly serving as a lead compound for developing treatments in areas like anxiety or depression.

An interesting aspect of this compound is its ionic nature as indicated by the chloride component, which can greatly influence its solubility and bioavailability. The interplay of the various functional groups can lead to unique pharmacokinetics and pharmacodynamics. Scientists often engage in structure-activity relationship (SAR) studies to determine which structural features contribute to desired biological effects.

In chemical research, compounds like this one serve as a rich source for understanding interactions at the molecular level. Some researchers state:

"Understanding the subtle variations in molecular structures provides insights not just into chemistry but into the intricate dance of life itself." – Anonymous

Thus, N-[phenyl-(1-piperidin-1-ium-1-ylcyclohexyl)methylene]acetamide; chloride continues to be a subject of interest, bridging organic synthesis with practical applications in therapeutics.

Synonyms
ACETAMIDE, N-(alpha-(1-PIPERIDINOCYCLOHEXYL)BENZILIDENE)-, MONOHYDROCHLORIDE
16297-43-1
N-((alpha-1-(1-Piperidino)cyclohexyl)benzilidene)acetamide monohydrochloride