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Thioacetamide

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Identification
Molecular formula
C2H5NS
CAS number
62-55-5
IUPAC name
N-phenyl-2-sulfanyl-acetamide
State
State

At room temperature, thioacetamide is in a solid state. It remains stable and intact under typical ambient conditions and does not exhibit volatility or significant reactivity with air or moisture.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.15
Boiling point (Celsius)
221.00
Boiling point (Kelvin)
494.15
General information
Molecular weight
105.15g/mol
Molar mass
105.1540g/mol
Density
0.9570g/cm3
Appearence

Thioacetamide appears as a white, crystalline solid. It is generally odorless and has a bitter taste. In its pure form, it maintains a uniform consistency and appearance, devoid of discoloration or impurities. Thioacetamide's crystalline structure contributes to its stability under standard conditions.

Comment on solubility

Solubility of N-phenyl-2-sulfanyl-acetamide

N-phenyl-2-sulfanyl-acetamide exhibits a unique solubility profile which can be influenced by various factors. The following points outline key aspects of its solubility:

  • Solvent Compatibility: This compound is generally more soluble in polar organic solvents, which facilitate interactions with its functional groups.
  • Water Solubility: While it may have limited solubility in water due to its hydrophobic phenyl group, the presence of the acetamide group can enhance solubility in certain conditions.
  • Temperature Dependencies: The solubility can significantly vary with temperature, often increasing with higher temperatures, making it crucial to consider this factor during experimentation.
  • pH Influence: The solubility is also impacted by the pH of the solution, reflecting the dissociation properties of the amide group under different acidic or basic conditions.

In conclusion, understanding the solubility of N-phenyl-2-sulfanyl-acetamide is essential for its application in various chemical processes. The intricate balance of its structural components and environmental conditions determines its solubility behavior.

Interesting facts

Interesting Facts About N-phenyl-2-sulfanyl-acetamide

N-phenyl-2-sulfanyl-acetamide, a compound that falls within the realm of organic chemistry, is a fascinating subject of study due to its unique structure and potential applications. Here are some captivating insights:

  • Structural Characteristics: This compound features a phenyl group attached to a sulfanyl (thiol) functional group, contributing to its distinct reactivity and properties.
  • Biological Relevance: Compounds like N-phenyl-2-sulfanyl-acetamide are of interest in medicinal chemistry. They may exhibit pharmacological activities that can be further explored for therapeutic purposes.
  • Potential Uses: The sulfanyl group is known for its ability to participate in various chemical reactions, making this compound a candidate for synthesis in organic reactions or as a building block in drug discovery.
  • Research Opportunities: Ongoing studies on thiol compounds have suggested their involvement in biochemical processes, indicating that N-phenyl-2-sulfanyl-acetamide may play a role in the development of antioxidant and antimicrobial agents.

As scientists continue to unravel the complexities of this compound, its significance in both laboratory settings and potential applications in drug development creates a rich field for exploration.

In the words of a fellow chemist, “The exploration of organic compounds is an endless journey of discovery, often leading to unexpected findings that challenge our understanding of chemistry.”

Synonyms
2-Mercaptoacetanilide
4822-44-0
2-Mercapto-N-phenylacetamide
Thioglycolanilide
Thioglycolic acid anilide
Acetamide, 2-mercapto-N-phenyl-
Acetanilide, 2-mercapto-
N-Phenyl-2-mercaptoacetamide
alpha-Mercaptoacetanilide
USAF EK-6583
.alpha.-Mercaptoacetanilide
NSC 2126
ACETANILIDE, alpha-MERCAPTO-
WB53BH5RKN
EINECS 225-398-5
BRN 2208086
N-PHENYLMERCAPTOACETAMIDE
DTXSID6048672
AI3-23887
NSC-2126
DTXCID9028598
4-12-00-00882 (Beilstein Handbook Reference)
Acetanilide, 2-mercapto-(8CI)
225-398-5
N-Phenyl-2-sulfanylacetamide
Thioglycolylanilide
MFCD00014451
Acetanilide, .alpha.-mercapto-
CHEMBL1993867
NCGC00160366-01
CAS-4822-44-0
NSC2126
UNII-WB53BH5RKN
WLN: SH1VMR
2-mercapto-N-phenyl-acetamide
N-phenyl-2-sulfanyl-acetamide
SCHEMBL253778
N-Phenyl-2-sulfanylacetamide #
ALBB-017010
Tox21_113043
BDBM50590253
STK397257
AKOS000313388
Tox21_113043_1
NCGC00160366-02
DB-051532
CS-0205992
NS00031780
EN300-199913
H31863
SR-01000945137
SR-01000945137-1
F0482-0001