Skip to main content

N-phenylaziridine-1-carboxamide

ADVERTISEMENT
Identification
Molecular formula
C9H10N2O
CAS number
1857-11-6
IUPAC name
N-phenylaziridine-1-carboxamide
State
State

At room temperature, N-phenylaziridine-1-carboxamide is in a solid state, typically forming crystalline structures.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.15
Boiling point (Celsius)
253.00
Boiling point (Kelvin)
526.15
General information
Molecular weight
176.21g/mol
Molar mass
176.2140g/mol
Density
1.2100g/cm3
Appearence

N-phenylaziridine-1-carboxamide is typically a white crystalline solid. It can appear as a powder or crystalline flakes, depending on the method of crystallization and the conditions under which it is stored.

Comment on solubility

Solubility of N-phenylaziridine-1-carboxamide

N-phenylaziridine-1-carboxamide exhibits selective solubility, influenced by its unique molecular structure. Understanding its solubility is essential for applications in synthesis and pharmaceutical development. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound generally shows moderate solubility in organic solvents such as methanol and ethanol, while exhibiting low solubility in water.
  • Hydrophobic and Hydrophilic Balance: The presence of the phenyl group contributes to its hydrophobic characteristics, which limits its interaction with polar solvents.
  • Temperature Dependence: Like many organic compounds, solubility may increase with higher temperatures, facilitating dissolution in less polar solvents.
  • Influence of pH: While primarily neutral, changes in pH can modify the compound’s solubility, particularly when considering ionization of the carboxamide functional group.

In summary, the solubility of N-phenylaziridine-1-carboxamide is moderate in organic solvents and limited in aqueous solutions, highlighting the complex interplay between molecular structure and solvent properties.

Interesting facts

Interesting Facts About N-phenylaziridine-1-carboxamide

N-phenylaziridine-1-carboxamide is an intriguing compound that plays a notable role in various fields of chemistry and pharmacology. This compound is particularly recognized for its unique aziridine structure, which consists of a three-membered nitrogen-containing ring. Here are some key points that highlight its significance:

  • Reactivity: The aziridine ring in N-phenylaziridine-1-carboxamide is highly reactive, making it a valuable intermediate in synthetic organic chemistry. It can undergo various reactions, including ring-opening and nucleophilic substitution.
  • Pharmaceutical Potential: Compounds containing aziridine moieties are often investigated for their biological activities. N-phenylaziridine-1-carboxamide may exhibit interesting pharmacological properties, including potential anticancer or antimicrobial activities.
  • Synthetic Applications: This compound can serve as a key starting material for the synthesis of more complex organic molecules. Its ability to act as a building block makes it an essential compound in the development of new pharmaceuticals.
  • Mechanistic Studies: The reactions of N-phenylaziridine-1-carboxamide and related compounds provide valuable insights into reaction mechanisms, aiding the understanding of how chemical transformations occur at a molecular level.
  • Research Opportunities: As a relatively less-studied compound, N-phenylaziridine-1-carboxamide presents numerous research opportunities for students and scientists interested in the fields of organic synthesis, medicinal chemistry, and materials science.

In summary, N-phenylaziridine-1-carboxamide is not just a simple compound; its reactivity and potential applications in medicine and synthesis are continuously being explored. As groups of research chemists delve into its properties, they may unlock new secrets and benefits that could lead to significant advancements in various scientific fields.

Synonyms
1-Aziridinecarboxanilide
Phenyl-N-carbamoylaziridine
1-AZIRIDINECARBOXAMIDE, N-PHENYL-
PQ4AW1DZ13
BRN 0123540
AI3-50171
NSC-50706
UNII-PQ4AW1DZ13
DTXSID40157800
5-20-01-00046 (Beilstein Handbook Reference)
1-Aziridinecarboxanilide (8CI)
DTXCID5080291
zypiazbahrutgu-uhfffaoysa-n
3-Phenyl-1,1-ethyleneurea
1-Phenylcarbamoylaziridine
N-Phenyl-N'-ethyleneurea
13279-22-6
N-(Phenylaminocarbonyl)aziridine
N-(Anilinocarbonyl)aziridine
N-Phenyl-1-aziridinecarboxamide
N-phenylaziridine-1-carboxamide
N,N-Ethylene-N'-phenylurea
NSC 50706
1-Aziridinecarboxamide,N-phenyl-(9CI)
1-(N-Phenylcarbamoyl)aziridine
aziridinyl-N-benzamide
N-phenylcarbamoylaziridine
WLN: T3NTJ AVMR
CHEMBL176956
SCHEMBL2897923
NSC50706
AKOS006241266
Aziridine-1-carboxylic acid phenylamide
ST51036432