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N-phenylbutanamide

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Identification
Molecular formula
C10H13NO
CAS number
541-48-0
IUPAC name
N-phenylbutanamide
State
State

At room temperature, N-phenylbutanamide is a solid.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.20
Boiling point (Celsius)
306.40
Boiling point (Kelvin)
579.60
General information
Molecular weight
163.22g/mol
Molar mass
163.2110g/mol
Density
1.0490g/cm3
Appearence

N-phenylbutanamide is typically a white crystalline solid.

Comment on solubility

Solubility of N-Phenylbutanamide

N-phenylbutanamide, a compound with the formula C11H15NO, exhibits interesting solubility characteristics that are influenced by its structural properties. Understanding the solubility of this compound is crucial for applications in various fields.

General Solubility Behavior

In general, the solubility of N-phenylbutanamide can be summarized as follows:

  • Solubility in Organic Solvents: N-phenylbutanamide is expected to be soluble in non-polar to moderately polar organic solvents, such as chloroform or benzene, due to its hydrophobic aromatic ring.
  • Solubility in Water: Its solubility in water is likely to be low because of the large hydrophobic component that can impede interactions with water molecules.

Factors Affecting Solubility

The solubility of N-phenylbutanamide can be influenced by various factors:

  1. Temperature: Increased temperatures typically enhance solubility in organic solvents.
  2. pH Levels: The presence of acidic or basic conditions may affect the ionization of the amide, potentially altering its solubility.
  3. Size of Solvent Molecules: The compatibility of solvent size with the compound's molecular structure plays a key role in solubility.

Thus, while N-phenylbutanamide showcases versatility in solubility with organic solvents, it remains largely insoluble in aqueous environments, an essential consideration for researchers and industry professionals alike. As a quote from a solubility study goes, "The interplay of hydrophilic and hydrophobic interactions determines the fate of compounds in solution."

Interesting facts

Interesting Facts about N-phenylbutanamide

N-phenylbutanamide, a member of the amide functional group, is an intriguing compound that showcases the fascinating interplay of organic chemistry and practical applications. As a molecular derivative of butyric acid, it is particularly noteworthy due to its structural versatility.

Key Features

  • Applications: This compound has attracted attention in the fields of pharmaceuticals and materials science. It is often explored for its potential uses in developing new drugs and as a building block for various organic syntheses.
  • Structural Significance: The presence of the phenyl group not only influences its reactivity but also enhances its solubility properties, making it a valuable compound for study in medicinal chemistry.
  • Biological Relevance: Compounds like N-phenylbutanamide are often assessed for their biological activities, which may include anti-inflammatory and analgesic properties, thus paving the way for innovative therapeutic agents.

Fun Fact

As a member of the amide family, N-phenylbutanamide exemplifies the concept of structure-activity relationship (SAR), helping chemists understand how small changes in molecular structure can drastically affect biological activity.

In Summary

With its unique chemical structure and potential applications, N-phenylbutanamide represents a vital area of study in organic chemistry. Whether you are a seasoned chemist or a student delving into organic synthesis, this compound provides ample opportunities for exploration and discovery!

Synonyms
Butanamide, N-phenyl-
Butyranilide
N-Phenylbutanamide
NSC 6123
EINECS 214-449-7
BRN 2207595
AI3-01391
DTXSID9061544
4-12-00-00387 (Beilstein Handbook Reference)
DTXCID8033308
214-449-7
ethylacetanilide
uhanvdzcdnsilx-uhfffaoysa-n
N-Phenylbutyramide
Butyrylanilide
n-Butyranilide
1129-50-6
Athylacetanilid
NSC6123
N-phenyl-butyramide
N-Phenylbutanamide #
WLN: 4VMR
SCHEMBL9888
SCHEMBL11591084
NSC-6123
AKOS003867742
DS-010542
NS00023668