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N-Phenylformamide

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Identification
Molecular formula
C7H7NO
CAS number
103-70-8
IUPAC name
N-phenylformamide
State
State
At room temperature, N-Phenylformamide remains in a solid crystalline state. However, upon slight heating, it can melt into a liquid that retains a clear, light appearance.
Melting point (Celsius)
46.50
Melting point (Kelvin)
319.65
Boiling point (Celsius)
257.00
Boiling point (Kelvin)
530.15
General information
Molecular weight
121.14g/mol
Molar mass
121.1400g/mol
Density
1.1393g/cm3
Appearence

N-Phenylformamide, also known as formanilide, is a solid compound that appears as colorless to pale yellow crystals. It may also be found in a liquid form when heated slightly, exhibiting low viscosity and an oily texture. Its crystalline structure at room temperature allows for a stable geometric form, often reflecting some degree of transparency.

Comment on solubility

Solubility of N-phenylformamide

N-phenylformamide, with the chemical formula C7H7NO, exhibits unique solubility characteristics that are important for its applications in various chemical processes.

In general, the solubility of N-phenylformamide can be summarized as follows:

  • Polar Solvents: N-phenylformamide is soluble in polar solvents such as water and ethanol. The presence of the amide group contributes to its ability to engage in hydrogen bonding, enhancing its solubility in such media.
  • Non-Polar Solvents: Conversely, it has limited solubility in non-polar solvents like hexane or benzene. This behavior is primarily due to the lack of significant interactions with the non-polar solvent molecules.
  • Temperature Dependency: Like many organic compounds, the solubility of N-phenylformamide can vary depending on temperature. Typically, increased temperatures lead to higher solubility.
  • pH Influence: The solubility can also be affected by the pH of the solution, with more acidic or alkaline conditions potentially altering its solubility profile.

It is important to note that while N-phenylformamide is generally categorized as a soluble compound in polar environments, its specific solubility can be subject to the influence of various environmental factors. Understanding these nuances is critical for efficient usage in chemical laboratories and industrial applications.

Interesting facts

N-Phenylformamide: An Insight into Its Significance

N-phenylformamide, often referred to as aniline formamide, is an intriguing compound that plays a vital role in both organic chemistry and pharmaceutical applications. It consists of a phenyl group attached to a formamide functional group, making it a versatile building block in the chemical industry.

Key Features and Applications

  • Versatile Intermediate: N-phenylformamide serves as an essential intermediate in synthesizing various organic compounds, especially in the pharmaceutical sector.
  • Biological Activity: This compound has demonstrated biological properties that attract interest in medicinal chemistry, particularly in the development of pharmacologically active molecules.
  • Research Importance: It is often used in research settings to explore reaction mechanisms and the formation of more complex organic structures.
  • Solvent Property: Due to its polar nature, N-phenylformamide can also act as a solvent in numerous organic reactions, aiding in the better solubility of reactants.

Why Chemists Are Fascinated

One of the compelling aspects of N-phenylformamide is its ability to undergo various chemical reactions, making it a significant subject of study. Chemists often explore its reactivity through:

  • Condensation Reactions: These reactions can lead to the formation of novel compounds that may showcase desirable properties.
  • Hydrolysis: Understanding the hydrolysis of N-phenylformamide can shed light on its stability and degradation pathways.
  • Resonance Structures: The delocalization of electrons in this molecule makes it an interesting example to study resonance, which is central to understanding many organic reactions.

In conclusion, N-phenylformamide stands out as a remarkable compound with significant implications in numerous chemical disciplines. Its unique structure and reactivity not only captivate chemists but also inspire ongoing research aimed at harnessing its potential in the synthesis of groundbreaking medicinal compounds.

Synonyms
Formanilide
N-PHENYLFORMAMIDE
103-70-8
N-Formylaniline
Formamide, N-phenyl-
Phenyl formamide
Formylaniline
Formamidobenzene
Carbanilaldehyde
Aniline, N-formyl-
N-phenyl-formamide
phenylformamide
CCRIS 4650
HSDB 5355
NSC 8862
EINECS 203-136-0
MFCD00003276
BRN 0906934
2805XEA9CL
DTXSID3025338
CHEBI:42416
AI3-01089
NSC-8862
FORMANILIDE [MI]
MLS002415732
DTXCID205338
N-PHENYLFORMAMIDE [HSDB]
4-12-00-00368 (Beilstein Handbook Reference)
SMR001370900
formanilid
forrnanilide
UNII-2805XEA9CL
NFormylaniline
N-Formanilide
Aniline, Nformyl
anilineformaldehyde
N-Formyl-aniline
n-phenyl formamide
N-phenylmethanamide
Formamide, Nphenyl
Formanilide, 99%
N-phenylformimidic acid
WLN: VHMR
cid_7671
SCHEMBL2463
BIDD:GT0244
ghl.PD_Mitscher_leg0.1270
CHEMBL1232659
SCHEMBL17211133
SCHEMBL25970875
BDBM74419
NSC8862
N-PHENYL FORMIC ACID, AMIDE
Tox21_200271
AKOS000297095
CS-W017768
NCGC00091354-01
NCGC00091354-02
NCGC00257825-01
AS-56859
CAS-103-70-8
SY011224
DB-040480
F0047
NS00023256
EN300-19846
D70279
AR-360/40233696
Q2689660
203-136-0
FAN