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N-Propyl-2-carboxamide-3,4-dihydro-2H-1,4-benzoxazine

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Identification
Molecular formula
C12H16N2O3
CAS number
219846-65-6
IUPAC name
N-propyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide
State
State

The compound is typically a solid at room temperature.

Melting point (Celsius)
159.50
Melting point (Kelvin)
432.65
Boiling point (Celsius)
436.00
Boiling point (Kelvin)
709.15
General information
Molecular weight
220.27g/mol
Molar mass
220.2650g/mol
Density
1.1189g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N-propyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide

N-propyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide, a complex organic compound, presents some intriguing characteristics with respect to its solubility. Several factors can influence its solubility, including:

  • Polarity: The structural features of benzoxazines often impart varying degrees of polarity, which can significantly affect solubility in polar versus non-polar solvents.
  • Hydrogen Bonding: The presence of carboxamide groups encourages hydrogen bonding, potentially enhancing solubility in water and other polar solvents.
  • Molecular Weight: The relatively high molecular weight can lead to lower solubility compared to smaller molecules.

In general, polar compounds like N-propyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide are typically more soluble in polar solvents (e.g., water, methanol) due to favorable interactions. Conversely, their solubility in non-polar solvents (e.g., hexane) tends to be significantly lower. As a rule of thumb, "like dissolves like," meaning that substances with similar polarities are more likely to dissolve in each other.

Overall, while specific solubility data for this compound may be limited, understanding the factors listed above can provide guidance on its expected solubility behavior in various environments.

Interesting facts

Interesting Facts about N-propyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide

N-propyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide is a fascinating compound with various applications and properties. Here are some intriguing insights:

  • Chemical Structure: This compound is an example of a benzoxazine, a class of heterocyclic compounds characterized by their unique ring structure. The incorporation of an amide group enhances its chemical reactivity and potential uses in organic synthesis.
  • Biological Activity: Benzoxazines have been researched for their biological activities, making N-propyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide of particular interest in medicinal chemistry. The compound's structure allows for interactions with biological targets, which could lead to the discovery of new pharmaceutical agents.
  • Synthetic Versatility: The synthesis of this compound can be achieved through various chemical pathways, making it a relevant topic in organic chemistry labs. Understanding the synthesis routes can highlight the principles of reaction mechanisms and functional group transformations.
  • Potential Applications: N-propyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide may have applications in fields such as material science and polymer chemistry. Its unique structure can be utilized in the development of advanced materials with specific properties.
  • Interdisciplinary Significance: The study of this compound is not just limited to chemistry; it spans across biology, materials science, and pharmacology, showcasing the interdisciplinary nature of modern scientific research.

In summary, N-propyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide serves as an excellent example of how intricate the world of chemical compounds can be, bridging various fields and offering limitless opportunities for discovery and innovation. As a chemist or student, delving deeper into such compounds can inspire future research and innovation.

Synonyms
22244-18-4
N-propyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide
DTXSID10274917
RefChem:831051
DTXCID40226368
999-727-2
N-Propyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxamide
HMS2171F07
MLS000566679
CHEMBL1518122
SCHEMBL17432607
HMS1730O06
HMS3316F12
MFCD06373520
AKOS000206330
AKOS017269865
NCGC00246114-01
SMR000153591
SY144661
CS-0223903
EN300-11699
G31495
Z57980698