Skip to main content

N-tert-butyl-4-isopropylsulfonyl-benzamide

ADVERTISEMENT
Identification
Molecular formula
C15H23NO3S
CAS number
622958-56-7
IUPAC name
N-tert-butyl-4-isopropylsulfonyl-benzamide
State
State

N-tert-butyl-4-isopropylsulfonyl-benzamide is typically a solid at room temperature. Its stable crystalline nature is suitable for handling as a powder or compacted solid in standard laboratory conditions.

Melting point (Celsius)
108.00
Melting point (Kelvin)
381.00
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.00
General information
Molecular weight
297.42g/mol
Molar mass
297.4210g/mol
Density
1.2100g/cm3
Appearence

N-tert-butyl-4-isopropylsulfonyl-benzamide appears as a white to off-white crystalline solid. The specific form and consistency can vary depending on the preparation and purity but it is typically observed in this powdery or granular solid state when pure.

Comment on solubility

Solubility of N-tert-butyl-4-isopropylsulfonyl-benzamide

N-tert-butyl-4-isopropylsulfonyl-benzamide, a compound with a complex structure, presents unique challenges regarding its solubility. Understanding its solubility characteristics is crucial, especially in the context of pharmaceutical applications. Here are some key points:

  • Solvent Dependence: The solubility of this compound may vary significantly depending on the solvent used. It is often more soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and acetone compared to water.
  • Temperature Influence: Like many organic compounds, an increase in temperature generally enhances its solubility. Thus, dissolving this compound at elevated temperatures might yield better results.
  • Polarity Effects: Given its sulfonyl and amide groups, which are polar, the solubility in polar solvents is somewhat expected, albeit limited. Non-polar solvents may exhibit poor solubility due to the hydrophilic nature of these functional groups.

In practical terms, if you're experimenting with N-tert-butyl-4-isopropylsulfonyl-benzamide, it is advisable to conduct solubility tests in various solvents to determine the optimal conditions for dissolution. This approach will not only save time but also enhance the efficiency of your research or application. Discover the right solvent, and you may unveil the full potential of this intriguing compound!

Interesting facts

Interesting Facts about N-tert-butyl-4-isopropylsulfonyl-benzamide

N-tert-butyl-4-isopropylsulfonyl-benzamide is a fascinating compound that falls within the realm of organic chemistry. Here are some engaging aspects of this compound:

  • Versatile Applications: This compound is often explored for its potential in pharmaceuticals and organic synthesis, particularly in drug development.
  • Sulfonyl Group Significance: The presence of the sulfonyl group (–SO₂) is noteworthy as it can enhance the compound's reactivity and influence its interactions with biological systems.
  • Structure and Properties: The unique combination of the tert-butyl and isopropyl groups contributes to the compound's steric hindrance, which can affect its reactivity and binding characteristics.
  • Research Potential: Chemists are interested in compounds like N-tert-butyl-4-isopropylsulfonyl-benzamide when exploring new methods for selective functionalization in organic reactions.
  • Importance in Medicinal Chemistry: Compounds that contain both a sulfonamide and an aromatic system are often studied for their biological activities, making them potential candidates for drug discovery.
  • Reaction Pathways: Due to the structure of this compound, it has been a subject of studies on various reaction pathways, such as electrophilic substitutions and nucleophilic attacks.

In summary, N-tert-butyl-4-isopropylsulfonyl-benzamide is more than just a structural entity; it embodies a variety of chemical functional properties that make it an intriguing subject for scientists and students alike. Its relevance in medicinal chemistry and organic synthesis sheds light on the profound implications of structural modifications in compound functionality.

Synonyms
N-tert-Butyl-p-(isopropylsulfonyl)benzamide
20884-75-7
BENZAMIDE, N-tert-BUTYL-p-(ISOPROPYLSULFONYL)-
DTXSID40175004
DTXCID6097495
RefChem:322534