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N-tert-butyl-4-methylbenzenesulfonimidic acid

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Identification
Molecular formula
C11H17NO2S
CAS number
39663-71-7
IUPAC name
N-tert-butyl-4-methyl-benzenesulfonimidic acid
State
State

At room temperature, N-tert-butyl-4-methylbenzenesulfonimidic acid is in a solid state, usually as a powder or crystalline solid.

Melting point (Celsius)
75.00
Melting point (Kelvin)
348.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
241.34g/mol
Molar mass
241.3390g/mol
Density
1.0200g/cm3
Appearence

N-tert-butyl-4-methylbenzenesulfonimidic acid typically appears as a colorless to pale yellow solid. The exact appearance can vary based on purity and form, such as crystalline or powder.

Comment on solubility

Solubility of N-tert-butyl-4-methyl-benzenesulfonimidic Acid

N-tert-butyl-4-methyl-benzenesulfonimidic acid is a compound that presents interesting solubility characteristics. Understanding its solubility is crucial for various applications in chemical processes and reactions.

Factors influencing the solubility of this compound include:

  • Polarity: The sulfonimidic acid functional group can increase polar interactions, potentially enhancing solubility in polar solvents.
  • Chain Length: The tert-butyl group contributes to hydrophobic interactions, which may decrease solubility in highly polar solvents but improve it in non-polar solvents.
  • Temperature: Like many organic compounds, solubility can vary significantly with changes in temperature, often increasing as temperature rises.

In general, it is expected that N-tert-butyl-4-methyl-benzenesulfonimidic acid will exhibit:

  • Moderate solubility in polar protic solvents such as water and alcohols.
  • Better solubility in non-polar organic solvents due to the presence of the bulky tert-butyl group.

As noted by researchers, “the balance between polar and non-polar characteristics largely determines solubility behavior,” making it essential to consider solvent choice when working with this compound.

In summary, N-tert-butyl-4-methyl-benzenesulfonimidic acid's solubility profile showcases its complex nature, influenced by both functional groups and overall molecular structure.

Interesting facts

Interesting Facts about N-tert-butyl-4-methyl-benzenesulfonimidic acid

N-tert-butyl-4-methyl-benzenesulfonimidic acid is a fascinating compound that showcases the intricate interplay between organic chemistry and pharmaceutical research. Here are some noteworthy aspects of this intriguing compound:

  • Versatility in Synthesis: This compound acts as an essential intermediate in the synthesis of various pharmaceuticals, making it a valuable resource in drug development.
  • Functional Groups: The presence of sulfonimidic acid functional groups enhances its reactivity and interactions with biological molecules, allowing for diverse applications.
  • Acid-Base Chemistry: Due to its acidic properties, N-tert-butyl-4-methyl-benzenesulfonimidic acid can participate in acid-base reactions, serving as a proton donor during chemical transformations.
  • Catalytic Role: This compound is often employed as a catalyst in synthetic organic chemistry, facilitating reactions that would otherwise be inefficient or difficult to achieve.
  • Biological Relevance: Some derivatives of this compound have been studied for their potential as antimicrobial agents, showing promise in the combat against resistant strains of bacteria.

As the renowned chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas." N-tert-butyl-4-methyl-benzenesulfonimidic acid exemplifies this ethos, inspiring chemists to explore new pathways and applications through its unique structure and reactivity. Whether in the lab or in the realm of pharmaceuticals, this compound certainly reflects the creativity and innovation inherent in modern chemistry.


Its continuing study enhances our understanding of functionalized sulfonamides and their roles in medicinal chemistry, making it a compound worthy of exploration for both students and seasoned scientists alike.

Synonyms
p-TOLUENESULFONAMIDE, N-(tert-BUTYL)-
NSC 59496
BRN 2112472
AI3-28468
4-11-00-00379 (Beilstein Handbook Reference)
Benzenesulfonamide, N-(1,1-dimethylethyl)-4-methyl-(9CI)
benzenesulfonamide, n-(1,1-dimethylethyl)-4-methyl-
N-tert-butyl-4-methylbenzenesulfonimidic acid