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Galanthamine

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Identification
Molecular formula
C17H21NO3
CAS number
357-70-0
IUPAC name
N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
State
State
At room temperature, Galanthamine exists as a solid. It is often stored in a tightly sealed container to prevent degradation from exposure to air or moisture.
Melting point (Celsius)
127.00
Melting point (Kelvin)
400.20
Boiling point (Celsius)
515.10
Boiling point (Kelvin)
788.30
General information
Molecular weight
287.38g/mol
Molar mass
287.3810g/mol
Density
1.2200g/cm3
Appearence
Galanthamine is typically isolated as a white solid, which can appear as an amorphous powder or crystalline solid. It might exhibit slight hygroscopic properties when exposed to moisture in the air.
Comment on solubility

Solubility of N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide (C17H21NO3)

N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide is a complex organic compound whose solubility characteristics may not be immediately apparent. Various factors influence the solubility of this compound, including:

  • Molecular Structure: The presence of bulky tert-butyl groups may hinder interaction with solvent molecules.
  • Polarity: With the presence of nitrogen and carbonyl groups, the compound may exhibit both polar and nonpolar characteristics, affecting its solubility in different solvents.
  • Solvent Type: Typically, compounds with similar polarities dissolve well together. This means it may be more soluble in organic solvents such as dimethyl sulfoxide (DMSO) or ethanol compared to water.

In general, solubility can be summarized as follows:

  • More soluble in organic solvents due to hydrophobic interactions.
  • Less soluble in water, which aligns with the common behavior of larger organic molecules.

Ultimately, conducting specific solubility tests under varied conditions can provide more precise insights regarding how this intriguing compound interacts with different solvents, as solubility can significantly differ based on temperature and pH as well.

Interesting facts

Interesting Facts about N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide

N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide is a fascinating compound that stands out in the field of organic chemistry not just for its complex structure, but also for its potential applications. Here are some key points about this intriguing compound:

  • Structural Complexity: The name itself reveals a highly intricate molecular framework, which is indicative of a rich variety of stereoisomers and reactivity patterns. The multi-cyclic nature of the compound suggests that it may participate in a variety of chemical reactions.
  • Biological Relevance: Compounds similar to this one are often investigated for their biological activities. They may exhibit properties such as anti-inflammatory, antibacterial, or even anticancer effects, making them worthy of further exploration.
  • Research Potential: Scientists are continuously exploring new compounds for pharmaceutical applications. The unique combination of functional groups in this compound could lead to the synthesis of novel drugs or therapeutic agents.
  • Chirality: The presence of asymmetric carbon centers contributes to chirality in this molecule, which can significantly influence the behavior of the compound in biological systems. Chirality is a crucial element in drug design, affecting efficacy and safety.
  • Environmental Impact: Understanding the behavior of such complex organic compounds can aid in assessing their environmental impact, particularly in the context of pharmaceutical residues in ecosystems.

As a chemistry student or scientist, exploring N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide offers a profound insight into the relationship between structure and function in organic molecules. The depth of study that such a compound invites cannot be overstated, making it an excellent candidate for both theoretical study and practical application.

Synonyms
1212235-84-1
N-tert-butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
5?-Finasteride
CHEMBL74318
SCHEMBL13609878
DTXSID60861154
4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5.alpha.,17.beta.)-
DBEPLOCGEIEOCV-UHFFFAOYSA-N
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(tert-butyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide
QFA37522
BBL009955
BDBM50025356
STK801358
AKOS005612990
NCGC00249055-01
AS-13023
N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
CS-0338683
EN300-19835710
N-tert-Butyl-3-oxo-4-aza-5.alpha.-androst-1-ene-17.beta.-carboxamide
N-(1,1-Dimethylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7- carboxamide
N-(tert-butyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
N-tert-butyl-2,15-dimethyl-5-oxo-6-azatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-3-ene-14-carboxamide
N-tert-butyl-4a,6a-dimethyl-2-oxo-1H,2H,4aH,4bH,5H,6H,6aH,7H,8H,9H,9aH,9bH,10H,11H,11aH-indeno[5,4-f]quinoline-7-carboxamide