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N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine

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Identification
Molecular formula
C14H18N2
CAS number
56698-50-7
IUPAC name
N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine
State
State

At room temperature, N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine is typically a solid. It maintains its crystalline structure under standard conditions, making it convenient for handling and storage.

Melting point (Celsius)
142.30
Melting point (Kelvin)
415.50
Boiling point (Celsius)
354.60
Boiling point (Kelvin)
627.80
General information
Molecular weight
235.31g/mol
Molar mass
235.3120g/mol
Density
1.1450g/cm3
Appearence

The compound is typically found in crystalline form. Its appearance can be described as colorless to pale yellow, depending on the degree of purity and specific synthesis methods utilized. As a solid, it is often available as small crystals or crystalline powder.

Comment on solubility

Solubility of N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine

The solubility of N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine (C14H18N2) can be considered within the context of organic compounds. Solubility tends to be governed by several key factors, which include:

  • Molecular Structure: The presence of both hydrophobic (tetralin moiety) and hydrophilic (amine group) regions in the molecule suggests variable solubility in different solvents.
  • Polarity: The molecule is expected to have moderate polarity due to the imidazole ring's ability to form hydrogen bonds, potentially enhancing solubility in polar solvents.
  • Solvent Interaction: N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine is likely to dissolve better in organic Polar Protic Solvents (e.g., methanol, ethanol) than in non-polar solvents.

While exact solubility values may vary, it is generally anticipated that:

  • The compound may be sparingly soluble in water due to its larger hydrophobic orbital structure.
  • It is likely more readily soluble in organic solvents such as ethanol, acetone, or dimethyl sulfoxide (DMSO).

In summary, understanding the solubility of N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine involves carefully considering its molecular interactions with different solvents. The balance between its polar and non-polar characteristics plays a significant role in determining how well it can dissolve in various media.

Interesting facts

Exploring N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine

N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine is a fascinating compound that belongs to the class of imidazoles, which have garnered interest for their diverse biological activities. Here are some intriguing facts about this compound:

  • Versatile Structure: The structure includes a tetralin moiety, which is known for its unique ring configuration, making it a useful scaffold in drug development.
  • Pharmacological Potential: Compounds within the imidazole family are often recognized for their roles in medicinal chemistry. They can act as antifungal, antiviral, and anticancer agents.
  • Synthesis Exploration: The synthesis of N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine typically involves multi-step reactions, showcasing the creativity required in synthetic organic chemistry.
  • Research Applications: This compound is a target for researchers aiming to understand the intricate interactions of various nitrogenous bases, providing insights into metabolic pathways.
  • Interdisciplinary Connections: The study of this compound connects fields such as pharmacology, medicinal chemistry, and organic synthesis, highlighting the interdisciplinary nature of modern scientific research.

As researchers continue to unravel the mysteries of imidazole derivatives, compounds like N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine stand at the forefront of innovative therapeutic exploration. Their unique structures and biological activities promise exciting opportunities for the design of new medicines.

Synonyms
Tramazoline
1082-57-1
Tramazolina
Rhinol
Tramazolinum
Muconasal
Rhynaspray
Tobispray
N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
Tramazoline [INN:BAN]
Tramazolinum [INN-Latin]
Tramazolina [INN-Spanish]
Muconasal (TN)
UNII-SLE31693IV
4,5-Dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-1H-imidazol-2-amine
Rhinospray
1H-Imidazol-2-amine, 4,5-dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-
Ellatun
Tramazoline (INN)
SLE31693IV
TRAMAZOLINE [MI]
EINECS 214-105-6
TRAMAZOLINE [INN]
TRAMAZOLINE [WHO-DD]
CHEMBL32573
Rhinol; Rhynaspray; Tobispray
DTXSID5046936
2-(5,6,7,8-tetrahydro-1-naphthylamino)-2-imidazoline
2-[(5,6,7,8-Tetrahydro-1-naphthyl)amino]-2-imidazoline
Tramazolinum (INN-Latin)
Tramazolina (INN-Spanish)
Imidazolidine,2-[(5,6,7,8-tetrahydronaphthal-1-yl]imino-
2-((5,6,7,8-TETRAHYDRO-1-NAPHTHYL)AMINO)-2-IMIDAZOLINE
tramazoline monohydrochloride
Imidazolidine,2-((5,6,7,8-tetrahydronaphthal-1-yl)imino-
SCHEMBL121944
SCHEMBL8623881
DTXCID3026936
R01AA09
CHEBI:134893
BCP29020
BDBM50027056
BDBM50225288
PDSP1_001098
PDSP2_001082
STL483756
DB13064
NS00004351
D08624
G46362
EN300-25745458
L000866
Q412102
2-(5,6,7, 8-tetrahydro-1-naphthylimino)-imidazolidine
2-(5,6,7,8-tetrahydro-1-naphthylimino)-imidazolidine
Imidazolidin-2-ylidene-(5,6,7,8-tetrahydro-naphthalen-1-yl)-amine
N-(5,6,7,8-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazol-2-amine #
(4,5-Dihydro-1H-imidazol-2-yl)-(5,6,7,8-tetrahydro-naphthalen-1-yl)-amine
2-imidazolin-2-yl(5,6,7,8-tetrahydro-1-naphthyl)amine tramazoline 2-(5,6,7,8-Tetrahydro-1-naphthylamino)-2-imidazoline 4,5-Dihydro-
214-105-6