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2-Acetamidothiazole

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Identification
Molecular formula
C5H6N2OS
CAS number
531-84-0
IUPAC name
N-thiazol-2-ylacetamide
State
State

2-Acetamidothiazole is typically found in a solid state at room temperature. It is often used in various chemical syntheses and can be stored in a dry and cool environment to maintain its stability.

Melting point (Celsius)
111.00
Melting point (Kelvin)
384.00
Boiling point (Celsius)
322.00
Boiling point (Kelvin)
595.00
General information
Molecular weight
142.18g/mol
Molar mass
142.1820g/mol
Density
1.2900g/cm3
Appearence

2-Acetamidothiazole appears as a white to off-white crystalline solid. The compound tends to be in a solid state at room temperature and can have a slight odor depending on the degree of purity and presence of other elemental compounds.

Comment on solubility

Solubility of N-thiazol-2-ylacetamide

N-thiazol-2-ylacetamide is a compound whose solubility characteristics are of particular interest in various applications. Its solubility can be influenced by several factors:

  • Polar and Non-polar Solvents: N-thiazol-2-ylacetamide shows varying degrees of solubility in polar and non-polar solvents due to the presence of both hydrophilic and hydrophobic groups.
  • Temperature: Increasing the temperature typically enhances solubility, making it a useful parameter in formulation processes.
  • pH Levels: The solubility may also be pH-dependent, as ionization of functional groups can alter the compound's accessibility in aqueous solutions.

Overall, it can be summarized that N-thiazol-2-ylacetamide possesses moderate solubility, demonstrating a solubility profile that can be leveraged in various chemical and biological contexts. It is essential to consider the specific conditions under which the compound is utilized to maximize its solubility and effectiveness in application.

Interesting facts

Interesting Facts About N-thiazol-2-ylacetamide

N-thiazol-2-ylacetamide is a fascinating chemical compound that has garnered attention in various fields, particularly in medicinal chemistry. Here are some compelling insights into this intriguing compound:

  • Bioactivity: N-thiazol-2-ylacetamide has demonstrated significant antibacterial and antifungal properties. Its unique thiazole moiety contributes to its biological activity, making it a potential candidate for the development of new antibiotics.
  • Synthesis: The synthesis of N-thiazol-2-ylacetamide often involves innovative methods that can include the reaction of thiazole derivatives with acetic anhydride or acetic acid. This synthetic pathway can serve as a model for developing other thiazole-based compounds.
  • Research Applications: This compound is not just limited to antimicrobial investigations; it's also studied for its potential roles in cancer therapy. Research suggests that thiazole rings can interact with various biological targets, possibly leading to groundbreaking treatments.
  • Structural Versatility: The distinct structure of N-thiazol-2-ylacetamide allows for modifications that can enhance its efficacy. Scientists frequently explore derivatives of this compound to improve its biological properties.
  • Pharmacological Significance: N-thiazol-2-ylacetamide's activity against certain pathogens highlights its potential use in pharmaceutical formulations. Ongoing studies aim to elucidate its mechanism of action further.

In summary, N-thiazol-2-ylacetamide stands out as a compound of strong interest within scientific research due to its promising bioactive properties and versatility in synthesis. The continuous investigation into its applications could lead to significant advancements in therapeutic strategies, particularly in fighting resistant microbial strains and cancer.

Synonyms
2-Acetamidothiazole
2719-23-5
2-Acetylaminothiazole
N-(1,3-Thiazol-2-yl)acetamide
Acetamide, N-2-thiazolyl-
2-Acetamido-1,3-thiazole
N-2-Thiazolylacetamide
Thiazole, 2-acetamido-
ACETAMIDE, N-(2-THIAZOLYL)-
EINECS 220-321-1
NSC 18750
NSC 44844
O94697VKTV
AI3-32922
NSC-18750
NSC-44844
DTXSID3062607
WXPLRSVMGRAIGW-UHFFFAOYSA-
DTXCID7037632
inchi=1/c5h6n2os/c1-4(8)7-5-6-2-3-9-5/h2-3h,1h3,(h,6,7,8)
N-(thiazol-2-yl)acetamide
154446-32-9
MFCD00016892
Acetamide, N-2(3H)-thiazolylidene-
2-Acetaminothiazole
N-Thiazol-2-ylacetamide
N-(2-Thiazolyl)acetamide
UNII-O94697VKTV
acetylamino thiazole
2-acetylamino thiazole
ACETAMIDOTHIAZOLE
N-2-thiazolyl acetamide
ACETAMIDE,N-2(3H)-THIAZOLYLIDENE-
Acetamide,N-2-thiazolyl-
2-Acetamidothiazole, 98%
N-(2-thiazolyl)-acetamide
SCHEMBL115951
NSC18750
NSC44844
AC7947
GEO-00020
N-(1,3-Thiazol-2-yl)acetamide #
STK054583
AKOS000279444
AKOS006223937
FA06274
FS-4269
SY049337
DB-014000
A1472
CS-0095600
NS00028269
2-Acetylaminothiazole;N-Thiazol-2-ylacetamide
AB-601/30915014
Q27285499
Z28173610
F0808-0926
WPY