Interesting facts
Understanding N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-acridin-9-yl)pentane-1,4-diamine
N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-acridin-9-yl)pentane-1,4-diamine is a complex organic compound notable for its involvement in medicinal chemistry and drug development. This compound has garnered interest due to several compelling factors:
- Targeting Cancer: The compound is modeled to function as a potent chemotherapeutic agent. The incorporation of chloroethyl groups suggests a mechanism that allows for the alkylation of DNA, potentially disrupting cancer cell division.
- Acridine Derivative: The presence of acridine in its structure may contribute to intercalation between DNA bases, enhancing its antiproliferative activity. Acridine derivatives are widely studied for their ability to inhibit cancer cell growth.
- Structure-Activity Relationship (SAR): Researchers are keen on analyzing how subtle modifications in its structure can affect the efficacy and selectivity of the compound against various tumor types. This can lead to more effective and less toxic treatment options.
- Potential Side Effects: While the therapeutic effects are promising, chemotherapeutics often come with significant side effects. Understanding the toxicity profiles is critical as it can inform dosage and administration in clinical settings.
- Future Research Directions: Ongoing studies are likely to explore the combinatorial use of this compound with other therapies to enhance its anticancer effectiveness while minimizing adverse effects. This aligns with the current trends in personalized medicine.
In summary, N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-acridin-9-yl)pentane-1,4-diamine stands at the intersection of synthetic chemistry and medical application, holding potential as a vital tool in the fight against cancer. As research progresses, it will be fascinating to watch how this compound may evolve within pharmacology and therapeutic design.
Synonyms
quinacrine mustard
64046-79-3
1-N,1-N-bis(2-chloroethyl)-4-N-(6-chloro-2-methoxyacridin-9-yl)pentane-1,4-diamine
8Y3YQP8GW6
1,4-Pentanediamine, N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-9-acridinyl)-
CHEBI:37595
N1,N1-bis(2-Chloroethyl)-N4-(6-chloro-2-methoxy-9-acridinyl)-1,4-pentanediamine
N(1),N(1)-bis(2-chloroethyl)-N(4)-(6-chloro-2-methoxyacridin-9-yl)pentane-1,4-diamine
N4-(6-Chloro-2-methoxyacridin-9-yl)-N1,N1-bis(2-chloroethyl)pentane-1,4-diamine
UNII-8Y3YQP8GW6
BRN 0056337
Acrichine Yperite
9-(4-(Bis-beta-chloroethylamino)-1-methylbutylamino)-6-chloro-2-methoxyacridine
ACRIDINE, 9-(4-(BIS(2-CHLOROETHYL)AMINO)-1-METHYLBUTYLAMINO)-6-CHLORO-2-METHOXY-
4-21-00-06249 (Beilstein Handbook Reference)
SCHEMBL4995822
CHEMBL1190232
DTXSID40982194
DB02240
NCI60_003038
Q27104415
ACRIDINE, 9-((4-(BIS(2-CHLOROETHYL)AMINO)-1-METHYLBUTYL)AMINO)-6-CHLORO-2-METHOXY-
N,N-Bis(2-chloroethyl)-4-[(6-chloro-2-methoxyacridin-9(10H)-ylidene)amino]pentan-1-amine
N1,N1-BIS(2-CHLOROETHYL-N4-(6-CHLORO-2-METHOXY-9-ACRIDINYL)-1,4-PENTANEDIAMINE
Solubility of N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-acridin-9-yl)pentane-1,4-diamine
The solubility of N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-acridin-9-yl)pentane-1,4-diamine in various solvents can exhibit notable characteristics due to its complex structure. Understanding its solubility behavior is crucial for applications across various fields, including pharmaceuticals. Here are some key points regarding its solubility:
In summary, the solubility of N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-acridin-9-yl)pentane-1,4-diamine is significantly influenced by the nature of the solvent and environmental conditions. Understanding these factors is essential for its effective use in practical applications.