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Deferiprone

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Identification
Molecular formula
C18H28N2O
CAS number
140-57-8
IUPAC name
N1,N1-diethyl-N4-(6-methoxy-8-quinolyl)pentane-1,4-diamine
State
State

This compound is typically a liquid at room temperature.

Melting point (Celsius)
-35.47
Melting point (Kelvin)
237.68
Boiling point (Celsius)
531.93
Boiling point (Kelvin)
805.08
General information
Molecular weight
312.45g/mol
Molar mass
312.4530g/mol
Density
1.1500g/cm3
Appearence

The compound typically appears as a clear, colorless to light yellow liquid.

Comment on solubility

Solubility of N1,N1-diethyl-N4-(6-methoxy-8-quinolyl)pentane-1,4-diamine

The solubility of N1,N1-diethyl-N4-(6-methoxy-8-quinolyl)pentane-1,4-diamine is influenced by several factors due to its complex structure. Here are some key points to consider:

  • Polarity: The presence of both polar amine groups and a non-polar hydrocarbon chain in this compound suggests a mixed polarity, which may lead to variable solubility in different solvents.
  • Solvent Interaction: It is likely to be more soluble in polar organic solvents such as ethanol and methanol, while having reduced solubility in non-polar solvents like hexane.
  • Hydrogen Bonding: The amine groups can engage in hydrogen bonding, which can enhance solubility in water compared to non-polar compounds.
  • Temperature Dependence: The solubility may increase with temperature, as is common with many organic compounds, due to increased molecular motion and disruption of intermolecular forces.

In summary, the solubility of N1,N1-diethyl-N4-(6-methoxy-8-quinolyl)pentane-1,4-diamine is likely to be variable and solvent-dependent, emphasizing the need for careful consideration in formulation applications.

Interesting facts

Interesting Facts about N1,N1-diethyl-N4-(6-methoxy-8-quinolyl)pentane-1,4-diamine

N1,N1-diethyl-N4-(6-methoxy-8-quinolyl)pentane-1,4-diamine is a fascinating compound with a variety of applications and intriguing properties that make it noteworthy in the field of chemistry.

Key Characteristics:

  • Pharmaceutical Potential: This compound is notably studied for its potential pharmacological properties, particularly as a possible therapeutic agent due to its structural analogies with various bioactive molecules.
  • Quinoline Moiety: The presence of the quinoline structure is significant, as this is a class of compounds widely recognized for their wide range of biological activities, including antimalarial and anticancer properties.
  • Mechanism Insights: Research suggests that the interactions of this compound with biological systems may provide insights into new treatment methodologies, particularly for complex diseases where conventional therapies fall short.

Moreover, the synthesis of N1,N1-diethyl-N4-(6-methoxy-8-quinolyl)pentane-1,4-diamine offers a unique opportunity to explore various synthetic routes and methodologies. As scientists delve into creating this compound, they face challenges that encourage innovation and application of advanced organic synthesis techniques.

Quote by Chemists:

As one prominent chemist noted, "The beauty of organic chemistry lies in the intricate and often undiscovered correlations between molecular structure and biological activity." This encapsulates the essence of why compounds like N1,N1-diethyl-N4-(6-methoxy-8-quinolyl)pentane-1,4-diamine are such a significant focus in ongoing research.

In conclusion, the exploration of this compound not only holds promise for future therapeutic developments but also enriches our understanding of molecular interactions within biological systems.

Synonyms
PAMAQUINE
Pamaquin
491-92-9
Plasmoquine
Praequine
Prequine
Plasmochin
Plasmocide
Beprochine
Aminoquin
Quipenyl
Gamefar
Pamaquine [INN]
CCRIS 6979
UNII-99QVL5KPSU
99QVL5KPSU
NSC 167382
NSC-167382
BRN 0027810
PAMAQUINE [MI]
N(1),N(1)-Diethyl-N(4)-(6-methoxy-8-quinolinyl)-1,4-pentanediamine
Plasmoquine [veterinary] (TN)
8-((4-(Diethylamino)-1-methylbutyl)amino)-6-methoxyquinoline
1,4-Pentanediamine, N1,N1-diethyl-N4-(6-methoxy-8-quinolinyl)-
4-22-00-05818 (Beilstein Handbook Reference)
Quinoline, 8-((4-(diethylamino)-1-methylbutyl)amino)-6-methoxy-
QUINOLINE, 6-METHOXY-8-(1-METHYL-4-DIETHYLAMINO)BUTYLAMINO-
Quinoline, 8-[[4-(diethylamino)-1-methylbutyl]amino]-6-methoxy-
Plasmoquine (veterinary)
1,4-Pentanediamine, N1,N1-diethyl-N4-(6-methoxy-8-quinolinyl)-(9CI)
QUINOLINE, 6-METHOXY-8-(1-METHYL-4-DIETHYLAMINO)BUTYLAMINO, METHYLENE-BIS-BETA-HYDROXYNAPHTHOATE
(+-)-pamaquine
einecs 211-224-5
n(sup 1),n(sup 1)-diethyl-n(sup 4)-(6-methoxyquinolin-8-yl)pentane-1,4-diamine pamoate
nsc 14220
pamachinum
pamaquina (inn-spanish)
pamaquina [inn-spanish]
pamaquine naphthoate [nf]
pamaquine pamoate [mi]
pamaquine, (+-)-
pamaquinum (inn-latin)
pamaquinum [inn-latin]
quinoline, 6-methoxy-8-(1-methyl-4-diethylamino)butylamino, methylene-bis-.beta.-hydroxynaphthoate
unii-96y4a9aodb
N1,N1-Diethyl-N4-(6-methoxy-8-quinolyl)-1,4-pentanediamine
MFCD00024026
(+/-)-PAMAQUINE
PAMAQUINE, (+/-)-
1-N,1-N-diethyl-4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
NSC167382
plasmoquin
N1,N1-diethyl-N4-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
NSC15016
SCHEMBL156942
CHEMBL472698
DTXSID90862331
CHEBI:135350
QTQWMSOQOSJFBV-UHFFFAOYSA-N
AC6214
SY248279
WLN: T66 BNJ HO1 JMY1&3N2&2
NS00041611
D02547
1, N1,N1-diethyl-N4-(6-methoxy-8-quinolinyl)-
Q3391724
8-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methoxy-quinoline
N1,N1-diethyl-N4-(6-methoxy-8-quinolyl)pentane-1,4-diamine
quinoline, 8-(4-diethylamino-1-methylbutylamino)-6-methoxy-