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Acridine Orange

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Identification
Molecular formula
C17H19N3
CAS number
65-61-2
IUPAC name
N1,N1,N7,N7-tetramethylacridine-1,7-diamine
State
State

At room temperature, Acridine Orange is in solid form.

Melting point (Celsius)
267.00
Melting point (Kelvin)
540.15
Boiling point (Celsius)
324.00
Boiling point (Kelvin)
597.15
General information
Molecular weight
265.35g/mol
Molar mass
265.3410g/mol
Density
1.1650g/cm3
Appearence

Acridine Orange appears as an orange solid in its powder form. It is a cationic dye that is often used in fluorescent staining procedures.

Comment on solubility

Solubility of N1,N1,N7,N7-tetramethylacridine-1,7-diamine (C17H19N3)

N1,N1,N7,N7-tetramethylacridine-1,7-diamine exhibits unique solubility characteristics influenced by its molecular structure.

The solubility of this compound can generally be described as follows:

  • Polar Solvents: It is likely to have limited solubility in highly polar solvents due to the hydrophobic nature of the acridine core.
  • Non-Polar Solvents: Conversely, N1,N1,N7,N7-tetramethylacridine-1,7-diamine tends to be more soluble in non-polar or slightly polar organic solvents like chloroform or ethyl acetate.
  • Hydrogen Bonding: The presence of amine groups may facilitate weak hydrogen bonding interactions, but these are unlikely to seriously enhance solubility in very polar media.

In conclusion, while N1,N1,N7,N7-tetramethylacridine-1,7-diamine has specific regions that could interact with polar solvents, its overall solubility profile suggests a preference for non-polar environments. As with many organic compounds, “like dissolves like” is an important rule to consider in predicting solubility. This insight can be useful for applications in synthesis and formulation where solubility plays a critical role.

Interesting facts

Interesting Facts about N1,N1,N7,N7-Tetramethylacridine-1,7-Diamine

N1,N1,N7,N7-Tetramethylacridine-1,7-diamine is a fascinating compound with a unique structure and diverse applications. This compound is a derivative of acridine, a compound noted for its heterocyclic aromatic properties. Here are some compelling insights about it:

  • Bioactivity: Acridine derivatives, including this tetramethyl-substituted variant, are known for their potential anti-cancer properties. Research suggests they may interfere with DNA processes, providing a unique mechanism in cancer treatment.
  • Synthesis: The synthesis of N1,N1,N7,N7-Tetramethylacridine-1,7-diamine involves complex organic reactions, highlighting the intricacies of organic synthesis techniques. Understanding these methods is crucial for chemists looking to explore similar compounds.
  • Applications: Beyond medicinal chemistry, this compound can also find applications in photodynamic therapy (PDT) where acridine derivatives have shown promise due to their ability to generate reactive oxygen species upon light activation.
  • Research Significance: The structure of the compound, with its multiple methyl groups, illustrates the influence of substituents on the biological activity of acridine. Studying such compounds helps researchers design better pharmaceuticals.
  • Structural Characteristics: The presence of both amine groups and methyl substitutions affects the solubility and interactiveness of the molecule, making it a subject of interest in theoretical and computational chemistry studies.

In the world of chemical research, compounds like N1,N1,N7,N7-Tetramethylacridine-1,7-diamine challenge scientists to explore the mechanisms of their action and develop innovative solutions using their unique properties. Each study undertaken with such compounds opens new doors in medical and material sciences.

Synonyms
SCHEMBL17423357
2,8-Di-(dimethylamino)-acridin