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N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide

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Identification
Molecular formula
C30H30N6O2
CAS number
102519-81-1
IUPAC name
N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide
State
State

At room temperature, this compound is a solid crystalline substance, known for its stability and low vapor pressure.

Melting point (Celsius)
260.00
Melting point (Kelvin)
533.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
482.55g/mol
Molar mass
482.5490g/mol
Density
1.2800g/cm3
Appearence

This compound typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide

The solubility of N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide, with the chemical formula C30H30N6O2, can be characterized by various key points:

  • Solvent Dependence: The solubility of this compound is significantly influenced by the choice of solvent. It tends to have higher solubility in organic solvents such as dimethyl sulfoxide (DMSO) or N,N-dimethylformamide (DMF).
  • Hydrophobic Nature: Due to its extensive aromatic structure, this compound is recognized for its hydrophobic characteristics, limiting its solubility in polar solvents like water.
  • Temperature Effect: As with many organic compounds, solubility may increase with temperature, allowing for better dissolution in chosen solvents.
  • Crystallinity: The presence of crystalline regions can also impact its solubility, with less crystalline forms typically being more soluble.

In summary, while N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide may present challenges in aqueous environments, it shows promising solubility profiles in appropriate organic solvents, showcasing the importance of structural and environmental factors in determining the solubility of chemical compounds.

Interesting facts

Exploring N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide

N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide, often referred to as a complex derivative in the realm of organic chemistry, presents intriguing possibilities and characteristics worth exploring. Here are some interesting aspects:

  • Structure and Functionality: This compound showcases a unique structure that combines both amide and pyrimidine functionalities, making it an excellent candidate for various biological and pharmaceutical applications.
  • Potential in Drug Development: The tetrahydropyrimidine moiety is known for its biological activity, particularly in the development of anti-cancer and antiviral agents. The extensive research surrounding compounds with similar structures can provide insights into this compound’s potential therapeutic benefits.
  • Material Science Applications: The rigidity of the phenyl and terephthalamide groups may contribute to interesting mechanical and thermal properties, making it a subject of interest in the development of new materials or polymers.
  • Synthetic Pathways: The creation of this compound involves strategic synthetic pathways that can inspire innovative methods in organic synthesis, showcasing the versatility of reaction mechanisms.
  • Intermolecular Interactions: Due to its complex structure, this compound may exhibit fascinating intermolecular interactions, influencing solubility, stability, and reactivity in various environments.

In conclusion, N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide is much more than just a chemical; it is a multidisciplinary entity bridging organic chemistry, medicinal research, and materials science. Understanding its properties opens doors to innovative applications and novel discoveries.

Synonyms
Terephthalanilide, 4',4''-bis(1,4,5,6-tetrahydro-2-pyrimidinyl)-
N,N'-Bis(4-(1,4,5,6-tetrahydro-2-pyrimidinyl)phenyl)-1,4-benzenedicarboxamide
553-36-6
GNF-Pf-5375
BRN 0771726
5-25-11-00055 (Beilstein Handbook Reference)
CHEMBL1198270
DTXSID50203822
1,4-Benzenedicarboxamide, N,N'-bis(4-(1,4,5,6-tetrahydro-2-pyrimidinyl)phenyl)-