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N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide dihydrochloride

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Identification
Molecular formula
C28H32Cl2N6O2
CAS number
1802613-31-5
IUPAC name
N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide;dihydrochloride
State
State

At room temperature, the compound exists in a solid state. It is typically stable under normal conditions but should be kept dry and stored in a suitable container to prevent degradation.

Melting point (Celsius)
260.00
Melting point (Kelvin)
533.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
612.11g/mol
Molar mass
612.1100g/mol
Density
1.2360g/cm3
Appearence

This compound typically appears as a crystalline solid, often characterized by its off-white to light yellow color, depending on impurities and formulation.

Comment on solubility

Solubility of N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide; dihydrochloride

The solubility of N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide; dihydrochloride (C28H32Cl2N6O2) can significantly influence its applications in various fields, particularly in pharmaceuticals and materials science.

Factors affecting its solubility include:

  • Polarity: The presence of functional groups such as amides and hydrochlorides can enhance solubility in polar solvents.
  • Hydrochloride Form: Being a dihydrochloride suggests increased solubility in water due to ionic interactions.
  • Temperature: Higher temperatures generally increase solubility for many compounds, although exceptions exist.
  • pH Levels: Altering the pH may convert the compound into different ionization states, potentially increasing solubility in specific media.

In practical terms, as a dihydrochloride, this compound will likely exhibit enhanced water solubility compared to its non-salt form. Its dissolved state can be crucial for bioavailability in pharmacological applications. Thus, understanding its solubility characteristics can lead to more effective formulations and uses.

In summary, the solubility properties of this compound highlight its versatility and importance in various chemical contexts, making it a subject worth exploring for researchers and industry professionals alike.

Interesting facts

Interesting Facts About N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide;dihydrochloride

N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide;dihydrochloride is a fascinating compound with significant implications in various fields of research, particularly in medicinal chemistry and materials science.

Key Characteristics

  • Dual Functionality: The compound features a unique structure with both amide linkages and tetrahydropyrimidine moieties, which often contributes to its biological activity.
  • Potential Biological Applications: Compounds like this one can exhibit antitumor, anti-inflammatory, and antimicrobial properties, making them candidates for drug development.
  • Structural Complexity: The tetracyclic structure of tetrahydropyrimidine plays a critical role in pharmacodynamics, affecting how the compound interacts with biological targets.

Interesting Insights

This compound is known for its ability to mimic certain biological structures, allowing it to effectively bind to target molecules. Such mimicry can enhance its therapeutic potential. According to research, compounds similar to this one can:

  • Interact with specific receptors in the body, thereby influencing biochemical pathways.
  • Modify enzyme activities, which can lead to various biological outcomes.
  • Exhibit selective toxicity towards cancer cells while sparing normal cells, a highly sought-after characteristic in oncology.

As scientists continue to explore the potential of compounds like N1,N4-bis[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]terephthalamide;dihydrochloride, they unlock new avenues for targeted therapies and innovation in materials science. With the growing interest in utilizing complex molecular structures in drug development, the future looks promising for this compound.

Synonyms
Phthalanilide 6
73-53-0
NSH4GY380P
NSC 57153
HR 2164
FDA 0090
4',4''-Bis(1,4,5,6-tetrahydro-2-pyrimidinyl)terephthalanilide dihydrochloride
Terephthalanilide, 4',4''-bis(1,4,5,6-tetrahydro-2-pyrimidinyl)-, dihydrochloride
1,4-Benzenedicarboxamide, N,N'-bis(4-(1,4,5,6-tetrahydro-2-pyrimidinyl)phenyl)-, dihydrochloride
NSC-57153
UNII-NSH4GY380P
DTXSID501018952
Q27285036
1,4-BENZENEDICARBOXAMIDE, N1,N4-BIS(4-(1,4,5,6-TETRAHYDRO-2-PYRIMIDINYL)PHENYL)-, HYDROCHLORIDE (1:2)