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Clonidine hydrochloride

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Identification
Molecular formula
C18H21Cl2N3OS
CAS number
5786-50-9
IUPAC name
N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]terephthalamide;dihydrochloride
State
State

Clonidine hydrochloride is typically in solid form at room temperature, existing as a crystalline powder.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.20
Boiling point (Celsius)
387.60
Boiling point (Kelvin)
660.80
General information
Molecular weight
284.56g/mol
Molar mass
266.5560g/mol
Density
1.5668g/cm3
Appearence

Clonidine hydrochloride generally appears as a white or off-white crystalline powder. This compound is noted for its crystalline nature, which exhibits significant purity and luminescent whitish coloration.

Comment on solubility

Solubility of N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]terephthalamide; dihydrochloride

The solubility of N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]terephthalamide; dihydrochloride can be characterized by several key factors:

  • Solvent Compatibility: This compound typically exhibits better solubility in polar solvents such as water and methanol due to its ionic nature as a dihydrochloride salt.
  • Temperature Influence: Solubility generally increases with temperature; thus, dissolving the compound in warm solvents may enhance its solubility.
  • pH Dependence: Solution pH can also affect solubility. In acidic conditions, the compound remains ionized and thus soluble, while in neutral to basic conditions, it might precipitate out.

In summary, the solubility of this compound is multifaceted and can be influenced by:

  1. Type of solvent
  2. Temperature of the solution
  3. pH of the environment

As with many organic compounds, understanding these factors is essential for optimizing its use in various applications. Thus, it is wise to consider these parameters while preparing solutions to ensure maximum efficacy and stability of N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]terephthalamide; dihydrochloride.

Interesting facts

Interesting Facts about N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]terephthalamide; dihydrochloride

This compound, with its intricate structure, represents a fascinating area of study within organic chemistry. Here are some compelling aspects to consider:

  • Complex Connectivity: The compound features a unique arrangement of imidazole and phenyl groups. This configuration may contribute to its potential applications in medicinal chemistry, including the development of pharmaceuticals or as a reagent in biochemical assays.
  • Interdisciplinary Applications: Its versatility allows for use in multiple fields, such as materials science, where this compound could serve as a building block for novel polymers or advanced materials. Investigations into its properties could lead to exciting discoveries.
  • Potential for Biological Activity: With imidazole rings being common in many biologically active molecules, it suggests that this compound may exhibit interesting interactions with biological pathways, making it a subject for pharmacological studies.
  • Research Challenges: The synthesis and characterization of this compound may present challenges due to its complex nature, offering an engaging topic for researchers exploring reaction mechanisms or purification techniques.

As you delve deeper into the study of N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]terephthalamide; dihydrochloride, consider the quote by famous chemist Robert H. Grubbs:

"Chemistry is the celebrated science of matter and its transformations..."

This emphasizes the transformative potential of such compounds in both academic and practical applications, encouraging a broad exploration of their capabilities.

Synonyms
NSC35843
HR 1886
SK 24759
N,N'-Bis[4-(imidazolin-2-yl)phenyl]-1,4-dicarbamoylbenzene
N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]terephthalamide