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N2-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide

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Identification
Molecular formula
C12H13NO4S3
CAS number
746640-10-2
IUPAC name
N2-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide
State
State
This compound is a solid at room temperature characterized by its powdery form and slight off-white to yellowish color.
Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
402.00
Boiling point (Kelvin)
675.15
General information
Molecular weight
356.43g/mol
Molar mass
356.4260g/mol
Density
1.3200g/cm3
Appearence

N2-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide typically appears as an off-white or yellowish powder. The compound is solid at room temperature, and its coloration may vary slightly depending on the specific conditions of storage and any impurities present.

Comment on solubility

Solubility of N2-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide

N2-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide, with the chemical formula C12H13NO4S3, exhibits **unique solubility characteristics** due to its complex molecular structure.

Understanding the solubility of this compound is crucial for its applications and behavior in various environments. Here are some key points to consider:

  • Polarity: The presence of sulfonamide groups significantly increases the polarity of the compound, leading to enhanced solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvents further contributes to a higher solubility, particularly in aqueous solutions.
  • Solvent Compatibility: While it is soluble in polar solvents, its solubility in non-polar solvents is expected to be low, which can influence its behavior in mixed solvent systems.
  • Concentration Dependence: Solubility can vary with concentration; as such, higher concentrations may lead to saturation effects in polar solvents.
  • Thermal Effects: Temperature may also play a role, as solubility generally increases with higher temperatures for many compounds.

In summary, the solubility of N2-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide is **highly dependent on factors** such as polarity, temperature, and the nature of the solvent. As noted, "solubility is a dance of molecular interactions", and for this compound, it performs an intricate choreography in polar environments.

Interesting facts

Interesting Facts about N2-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide

N2-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide is a fascinating compound that showcases the intersection of organic chemistry and medicinal applications. Its complex structure, featuring thiophene and sulfonamide moieties, invites deeper exploration into its potential uses and properties.

Key Characteristics

  • Sulfamoyl Groups: The presence of sulfonamide functional groups in the compound enhances its solubility and biological activity, making it a good candidate for further pharmaceutical exploration.
  • Electron-Donating Effects: The 4-methoxy group on the phenyl ring serves as an electron-donating group, which could modulate the electronic properties of the compound and affect its reactivity and stability.
  • Diverse Applications: Compounds that contain thiophene rings are prominently studied for their applications in organic semiconductors, solar cells, and as potential antiviral agents.

Potential Biological Significance

This sulfonamide derivative has sparked interest due to its possible effects on biological systems. Research into similar compounds has shown that:

  • They can exhibit anti-inflammatory properties, providing a pathway for the development of new therapeutic agents.
  • Some thiophene derivatives have demonstrated antibacterial activity, leading to their exploration as alternatives to traditional antibiotics.
  • Given the structural diversity of sulfonamides, this compound could lead to breakthroughs in drug design, specifically in targeting microbial infections.

Ultimately, the investigation of N2-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide contributes to the ongoing quest for novel compounds with enhanced efficacy and reduced side effects in pharmaceuticals. Its intriguing structure and potential applications make it a subject of enduring scientific interest.

Synonyms
AL5927
n-[(4-methoxyphenyl)methyl]2,5-thiophenedesulfonamide
N2-((4-methoxyphenyl)methyl)thiophene-2,5-disulfonamide
N2-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide
2-N-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide
1bn4
N-(4-methoxybenzyl)thiophene-2,5-disulfonamide
AL9
SCHEMBL680127
BDBM11930
DB03526
NS00068981
Q27094465