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Ecamsule

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Identification
Molecular formula
C28H34N2O8S2
CAS number
92761-26-7
IUPAC name
N3-[(1-ethylpyrrolidin-2-yl)methyl]-4-methoxy-benzene-1,3-dicarboxamide
State
State

At room temperature, Ecamsule is in a solid state. It is typically found as a powder and used in its solid form within various sun protection formulations. Due to its nature, it is often integrated into lotions or creams to leverage its photocatalytic properties. The solid state facilitates its stability and efficacy as a UV filter in formulated products.

Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
268.00
Boiling point (Kelvin)
541.15
General information
Molecular weight
563.58g/mol
Molar mass
563.5780g/mol
Density
1.3500g/cm3
Appearence

Ecamsule is typically a white to very light beige powder. It can appear as a crystalline solid, often used in fine powder form for formulation into various sun care products. Its appearance is consistent with many organic compounds used in cosmetic formulations. The compound is often formulated in suspension due to its powdery form, facilitating its use as an active ingredient in sunscreens.

Comment on solubility

Solubility of N3-[(1-ethylpyrrolidin-2-yl)methyl]-4-methoxy-benzene-1,3-dicarboxamide

N3-[(1-ethylpyrrolidin-2-yl)methyl]-4-methoxy-benzene-1,3-dicarboxamide presents intriguing solubility characteristics that are worth discussing.

Due to its unique structure, the compound exhibits varying solubility in different solvents:

  • Apolar solvents: Generally, this compound may have limited solubility, as the presence of polar functional groups can hinder interaction with nonpolar solvents.
  • Polar solvents: The solubility tends to increase significantly in more polar solvents such as water, dimethyl sulfoxide (DMSO), and ethanol. This is attributed to the ability of the polar functional groups to interact favorably with the solvent molecules.

The interplay of these factors leads to the conclusion that:

  • Temperature and pressure: Increasing temperature often enhances solubility for many organic compounds, thus may apply here.
  • pH variations: Being a dicarboxamide, changes in pH can also influence solubility due to potential ionization of functional groups.

Overall, while N3-[(1-ethylpyrrolidin-2-yl)methyl]-4-methoxy-benzene-1,3-dicarboxamide may not be universally soluble, it demonstrates significant solubility in suitable polar environments, showcasing the fascinating nature of solubility in chemical compounds.

Interesting facts

Interesting Facts about N3-[(1-ethylpyrrolidin-2-yl)methyl]-4-methoxy-benzene-1,3-dicarboxamide

N3-[(1-ethylpyrrolidin-2-yl)methyl]-4-methoxy-benzene-1,3-dicarboxamide is a fascinating compound with several intriguing characteristics that make it notable in the field of chemistry:

  • Potential Applications: This compound is primarily researched for its potential applications in medicinal chemistry. The unique combination of a pyrrolidine structure and a 1,3-dicarboxamide moiety suggests possible activity pertinent to drug discovery.
  • Structural Complexity: With its multi-functional groups, including methoxy and dicarboxamide, this compound exhibits a rich chemical architecture that may contribute to diverse interactions at the molecular level, making it a significant candidate for further investigation.
  • Bioactivity: The presence of a pyrrolidine ring is crucial, as pyrrolidines are often found in various bioactive natural products and pharmaceuticals, which underlines the compound's potential pharmacological significance.
  • Research Insights: Studies have shown that compounds similar to this one may exhibit enhanced lipophilicity, allowing for better permeability through biological membranes, which is a vital attribute for drug candidates.
  • Novelty in Synthesis: The synthetic pathways to form such complex molecules are continually being optimized, showcasing the ingenuity of chemists in manipulating various reactions to obtain desired substances. This route of synthesis itself stands as a testament to chemical innovation.

As we delve deeper into the properties and interactions of N3-[(1-ethylpyrrolidin-2-yl)methyl]-4-methoxy-benzene-1,3-dicarboxamide, we find that it not only enriches our understanding of organic chemistry but also opens avenues for advancements in medicinal applications. The interplay of its structural elements beckons further exploration, ultimately pushing the boundaries in the fields of chemistry and pharmacology.

Synonyms
23694-34-0
BRN 0427404
G-297
N-(1-Ethyl-2-pyrrolidinylmethyl)-6-methoxyisophthalamide
1-Etil-2-(2'-metossi-5'-carbamoilbenzamidometil)-pirrolidina [Italian]
ISOPHTHALAMIDE, N-(1-ETHYL-2-PYRROLIDINYLMETHYL)-6-METHOXY-
1,3-Benzenedicarboxamide, N(sup 3)-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxy-
1-Etil-2-(2'-metossi-5'-carbamoilbenzamidometil)-pirrolidina
RefChem:349779
N1-((1-Ethylpyrrolidin-2-yl)methyl)-6-methoxyisophthalamide
DTXSID00946499
N~3~-[(1-Ethylpyrrolidin-2-yl)methyl]-4-methoxybenzene-1,3-dicarboximidic acid