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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
N,3-dimethyl-5-(5-nitro-2-furyl)isoxazole-4-carboxamide
State
State

At room temperature, Nitrofurazone is in a solid state. It is often manipulated and stored as a dry powder.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
504.30
Boiling point (Kelvin)
777.45
General information
Molecular weight
198.16g/mol
Molar mass
198.1570g/mol
Density
1.6800g/cm3
Appearence

Nitrofurazone typically appears as a yellow crystalline solid. It is known for its bright yellow color, which is characteristic for many nitro compounds. The compound is available in powder form and may have a slightly bitter odor.

Comment on solubility

Solubility Characteristics of N,3-Dimethyl-5-(5-nitro-2-furyl)isoxazole-4-carboxamide

The solubility of N,3-dimethyl-5-(5-nitro-2-furyl)isoxazole-4-carboxamide is an intriguing aspect worth exploring due to its unique structural features. Understanding its solubility can provide insights into its practical applications and behaviors in various solvents.

Key Solubility Insights:

  • Polar vs. Nonpolar Solvents: This compound displays a varied solubility profile, often dissolving better in polar solvents due to the presence of polar functional groups such as the carboxamide.
  • Temperature Dependency: Like many organic compounds, its solubility can significantly increase with temperature, reflecting a common phenomenon where solubility is positively correlated with increased thermal energy.
  • Impact of pH: The solubility may also be influenced by the pH of the solution, especially considering the carboxamide group that can vary in protonation under different pH conditions.
  • Hydrogen Bonding: The potential for hydrogen bonding in this compound can enhance solubility in water by stabilizing intermolecular interactions.

In conclusion, the solubility behavior of N,3-dimethyl-5-(5-nitro-2-furyl)isoxazole-4-carboxamide is significantly determined by its polar characteristics, environmental factors, and molecular interactions. This complexity makes solubility a pivotal consideration for further research and practical applications of this compound.

Interesting facts

Interesting Facts about N,3-Dimethyl-5-(5-Nitro-2-furyl)isoxazole-4-carboxamide

N,3-Dimethyl-5-(5-nitro-2-furyl)isoxazole-4-carboxamide, often abbreviated in discussions as DMNFICA, is a fascinating compound in the realm of medicinal chemistry and organic synthesis. Here are some engaging facts about this intriguing chemical:

  • Unique Structure: The isoxazole ring in DMNFICA contributes to its unique properties, blending an aromatic character with a heterocyclic structure. This gives rise to interesting electronic characteristics and potential reactivity.
  • Medicinal Potential: Compounds featuring nitrofuran derivatives have garnered attention in pharmacology. DMNFICA is studied for its potential therapeutic applications, such as in antimicrobial and antitumor activities, showcasing the importance of n-substituted isoxazoles in drug discovery.
  • Synthetic Pathways: The synthesis of DMNFICA can involve various innovative methods, strengthening the importance of synthesis strategies in organic chemistry. A combination of various reactions, such as nucleophilic substitutions and cycloadditions, often plays a crucial role in constructing this compound.
  • Research Applications: DMNFICA serves as a valuable building block for further chemical modifications. Researchers often explore its derivatives to enhance bioactivity or to modify properties for specific applications.
  • Interdisciplinary Relevance: The compound finds relevance across multiple scientific disciplines. Its study and applications span from organic chemistry to pharmacology and material science, making it a compound of interest in interdisciplinary research.

In summary, N,3-dimethyl-5-(5-nitro-2-furyl)isoxazole-4-carboxamide exemplifies the intersection of complex organic chemistry with meaningful biomedical applications. The ongoing research surrounding its properties and behaviors continues to shed light on its potential utilities, emphasizing the importance of studies in novel compound synthesis and characterization.

Synonyms
4-ISOXAZOLECARBOXAMIDE, N,3-DIMETHYL-5-(5-NITRO-2-FURYL)-
N,3-Dimethyl-5-(5-nitro-2-furyl)-4-isoxazolecarboxamide
21787-35-9
DTXSID60176194
RefChem:293696
DTXCID0098685