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Amodiaquine

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Identification
Molecular formula
C20H22ClN3O
CAS number
86-42-0
IUPAC name
N4-(2-chloro-7-methoxy-acridin-9-yl)-N1,N1-diethyl-pentane-1,4-diamine
State
State

The compound is a solid at room temperature, typically found as a crystalline powder.

Melting point (Celsius)
200.80
Melting point (Kelvin)
473.95
Boiling point (Celsius)
314.30
Boiling point (Kelvin)
587.45
General information
Molecular weight
355.87g/mol
Molar mass
355.8720g/mol
Density
1.3484g/cm3
Appearence

Amodiaquine appears as a yellow powder. It is sparingly soluble in water and freely soluble in chloroform.

Comment on solubility

Solubility of N4-(2-chloro-7-methoxy-acridin-9-yl)-N1,N1-diethyl-pentane-1,4-diamine

The solubility of N4-(2-chloro-7-methoxy-acridin-9-yl)-N1,N1-diethyl-pentane-1,4-diamine can be influenced by several factors due to its complex structure. Understanding its solubility is crucial for applications in pharmaceuticals or materials science. Below are key points regarding its solubility:

  • Polarity : The presence of both polar and non-polar functional groups suggests that this compound may exhibit variable solubility in different solvents.
  • Solvent Compatibility : It is likely to be soluble in organic solvents such as ethanol or DMSO, while exhibiting lower solubility in highly polar solvents like water.
  • pH Sensitivity : The solubility may also change with pH due to the presence of amine groups, which can become protonated in acidic conditions, altering solubility characteristics.
  • Temperature Effects : Increased temperature generally enhances solubility; therefore, experimenting with temperature variations might yield interesting results.

As a general observation, the complex nature of this compound may lead to unique solubility properties that could be tailored for specific applications by adjusting solvent types and conditions. Exploration into its solubility behavior can open avenues for innovative uses in various chemical and biological systems.

Interesting facts

Interesting Facts about N4-(2-chloro-7-methoxy-acridin-9-yl)-N1,N1-diethyl-pentane-1,4-diamine

This compound belongs to a class of molecules known as aryl amines, which are often utilized for their potential pharmaceutical properties. Below are some engaging points about this intriguing compound:

  • Versatile Structure: The presence of a methoxy group and a chloro substituent on the acridine ring makes this compound particularly interesting for chemists working on drug design and synthesis.
  • Biological Relevance: Compounds structurally similar to this one have shown potential in various biological activities, making them candidates for research in therapeutic applications, especially in oncology.
  • Mechanisms of Action: The unique arrangement of functional groups may allow this compound to interact with various biological targets, offering a pathway for drug development that can potentially lead to new treatments.
  • Importance of Substituents: The chlorinated and methoxylated groups can significantly affect the compound’s reactivity and overall biological efficacy, showcasing the importance of structure-function relationships in medicinal chemistry.
  • Complex Synthesis: The synthesis of such multi-substituted aromatic amines often requires advanced knowledge of organic synthesis techniques, highlighting the challenges faced by chemists in materials design.

In summary, N4-(2-chloro-7-methoxy-acridin-9-yl)-N1,N1-diethyl-pentane-1,4-diamine exemplifies how small changes in chemical structure can lead to vastly different properties and potential applications in the field of medicinal chemistry. It serves as a vivid reminder of the intricate link between chemistry and biology.

Synonyms
Cellulose, carboxymethyl ether, calcium salt
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