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N4-(3-bromophenyl)-N7-methyl-quinazoline-4,6,7-triamine

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Identification
Molecular formula
C15H13BrN6
CAS number
.
IUPAC name
N4-(3-bromophenyl)-N7-methyl-quinazoline-4,6,7-triamine
State
State

This compound is typically a solid at room temperature, usually found as a powder or crystalline substance.

Melting point (Celsius)
259.00
Melting point (Kelvin)
532.15
Boiling point (Celsius)
489.00
Boiling point (Kelvin)
762.15
General information
Molecular weight
316.21g/mol
Molar mass
316.1870g/mol
Density
1.6000g/cm3
Appearence

N4-(3-bromophenyl)-N7-methyl-quinazoline-4,6,7-triamine appears as a crystalline solid. The color and texture can vary depending on its specific form, but it is generally a powder or crystalline aggregate.

Comment on solubility

Solubility of N4-(3-bromophenyl)-N7-methyl-quinazoline-4,6,7-triamine

N4-(3-bromophenyl)-N7-methyl-quinazoline-4,6,7-triamine (C15H13BrN6) showcases unique solubility characteristics due to its complex molecular structure. When evaluating solubility, several factors come into play:

  • Polarity: The presence of multiple nitrogen atoms typically leads to greater polarity, which can enhance solubility in polar solvents like water.
  • Functional Groups: The bromophenyl group may impart hydrophobic properties, influencing its solubility profile.
  • Solvent Interaction: This compound may exhibit differential solubility in organic solvents versus aqueous solutions, favoring non-polar solvents for better dissolution.
  • Temperature Dependence: Solubility can vary significantly with temperature, often increasing at elevated temperatures.

In practice, one might observe the following behavior:

  1. High solubility in dimethyl sulfoxide (DMSO), which is beneficial for biological applications.
  2. Limited solubility in water, potentially complicating formulation strategies in pharmaceutical contexts.
  3. Variable results in different organic solvents, further emphasizing the necessity for solvent selection based on intended use.

Overall, understanding the solubility of N4-(3-bromophenyl)-N7-methyl-quinazoline-4,6,7-triamine is crucial for its practical applications, particularly in drug development and formulation science. Scientists often conduct solubility tests to identify the most effective solvents for optimal use.

Interesting facts

Interesting Facts about N4-(3-bromophenyl)-N7-methyl-quinazoline-4,6,7-triamine

N4-(3-bromophenyl)-N7-methyl-quinazoline-4,6,7-triamine is a fascinating compound, particularly due to its implications in medicinal chemistry. Here are some noteworthy points:

  • Biological Activity: This compound belongs to the quinazoline family, known for their diverse biological activities, including anti-cancer, anti-inflammatory, and antimicrobial properties. Such compounds are often studied for their potential therapeutic effects.
  • Bromine Substitution: The presence of a bromine atom in this compound significantly alters its chemical behavior and enhances its reactivity. Brominated compounds can be particularly interesting in the realm of medicinal chemistry for their ability to interact with biological targets.
  • Structure-Activity Relationship (SAR): The unique arrangement of functional groups in this compound allows researchers to explore SAR, which is critical for developing more effective pharmaceuticals. By modifying components, scientists aim to enhance potency and reduce side effects.
  • Research Applications: Compounds like this one are often used in synthesis and development processes to create analogs that might be more effective in specific applications, such as cancer treatment or neurological disorders.
  • Quinazoline Derivatives: The quinazoline framework has garnered interest due to its prevalence in various bioactive compounds. Exploring the modifications in this structure can unveil new therapeutic avenues and facilitate the design of next-generation drugs.

In summary, N4-(3-bromophenyl)-N7-methyl-quinazoline-4,6,7-triamine exemplifies the intricate link between structure and pharmacological action, making it a significant subject for ongoing research in the pharmaceutical sciences.

Synonyms
CHEMBL92937
6-Amino-4-[(3-bromophenyl)amino]-7-(methylamino)quinazoline
BDBM3544
4-N-(3-bromophenyl)-7-N-methylquinazoline-4,6,7-triamine
HSCI1_000068
BRD-K43030839-001-01-6