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Nifuroxazide

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Identification
Molecular formula
C12H9N3O5
CAS number
965-52-6
IUPAC name
N,5-dimethyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide
State
State

At room temperature, Nifuroxazide is typically a solid. It is stable under ordinary conditions of use and storage. Its crystalline powder form ensures that it remains in the solid state at room temperature.

Melting point (Celsius)
201.00
Melting point (Kelvin)
474.15
Boiling point (Celsius)
364.00
Boiling point (Kelvin)
637.15
General information
Molecular weight
275.21g/mol
Molar mass
275.2300g/mol
Density
1.6200g/cm3
Appearence

Nifuroxazide appears as a yellow crystalline powder. It is typically produced in this form for use in both pharmaceutical and clinical applications. Its yellow color is characteristic and is usually quite vivid, giving it a distinct appearance.

Comment on solubility

Solubility of N,5-dimethyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide

The solubility of N,5-dimethyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide in various solvents can play a significant role in its applications and effectiveness. Understanding its solubility characteristics is essential for optimizing its use in different chemical environments.

Solubility Characteristics:

  • Solvent Polarity: The polarity of solvents significantly influences the solubility of this compound. Increased polarity typically enhances solubility for polar compounds.
  • Functional Groups: The presence of the isoxazole and carboxamide groups can affect solubility. Carboxylic acid derivatives often exhibit good solubility in water due to hydrogen bonding capabilities.
  • Temperature Dependence: Higher temperatures often increase solubility. Thus, evaluating solubility at varying temperatures is crucial for practical applications.
  • pH Influence: Since this compound contains acidic and potentially basic functional groups, its solubility may vary with changes in pH, impacting its behavior in different environments.

To sum up, while the specific solubility of N,5-dimethyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide requires empirical data for precise understanding, considering the above factors can provide insight into its soluble nature. As the quote goes, “The solvent is often as important as the solute.”
Generally, the successful utilization of this compound will depend on a thorough exploration of its solubility profile in various conditions.

Interesting facts

Interesting Facts about N,5-dimethyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide

N,5-dimethyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide is a fascinating compound that has drawn attention for its unique structural characteristics and potential applications in various fields of research.

Structural Highlights

  • Isoxazole Ring: This compound features an isoxazole ring, a five-membered heterocyclic structure containing both nitrogen and oxygen. This ring system is known for its diverse biological activities.
  • Nitro Group: The presence of the nitro functional group contributes to the electron-withdrawing properties of the compound, enhancing its reactivity and potential for forming various derivatives.
  • Dimethyl Substitution: The dimethyl substitutions at the nitrogen atom provide steric hindrance, which can influence the compound's interaction with biological targets, making it an interesting subject for medicinal chemistry.

Applications and Significance

This compound is particularly noteworthy due to several potential applications:

  • Pharmaceutical Research: Its structural properties suggest it could serve as a lead compound in the development of new pharmaceuticals, particularly in targeting microbial infections and cancerous cells.
  • Agricultural Chemistry: The compound may also find a role in agrochemicals, where its reactivity could be leveraged to create safer and more effective pesticides or herbicides.
  • Material Science: The unique characteristics of the isoxazole moiety can lead to the development of novel materials with interesting electronic or optical properties.

Conclusion

The exploration of N,5-dimethyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide opens up avenues in both synthetic and applied chemistry. Its complex structure, coupled with varied potential applications, makes it a compelling subject for further study and promotes a deeper understanding of isoxazole chemistry.

Synonyms
21787-34-8
N,5-Dimethyl-3-(5-nitro-2-furyl)-4-isoxazolecarboxamide
DTXSID00176193
4-ISOXAZOLECARBOXAMIDE, N,5-DIMETHYL-3-(5-NITRO-2-FURYL)-
RefChem:293697
DTXCID5098684