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Naphthalene-1-carboxylic acid oxime

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Identification
Molecular formula
C11H9NO2
CAS number
2243-59-2
IUPAC name
naphthalene-1-carbohydroxamic acid
State
State

At room temperature, Naphthalene-1-carboxylic acid oxime is typically in a solid state.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.00
Boiling point (Celsius)
344.00
Boiling point (Kelvin)
617.00
General information
Molecular weight
171.19g/mol
Molar mass
171.1910g/mol
Density
1.3207g/cm3
Appearence

Naphthalene-1-carboxylic acid oxime typically appears as a white to light beige crystalline solid. It can sometimes appear in other light colors when impurities are present.

Comment on solubility

Solubility of Naphthalene-1-Carbohydroxamic Acid

Naphthalene-1-carbohydroxamic acid is a compound that exhibits interesting solubility characteristics. The solubility of this compound can be influenced by several factors:

  • Polar and Nonpolar Solvent Interaction: Due to the presence of both polar hydroxyl groups and nonpolar naphthalene rings, naphthalene-1-carbohydroxamic acid shows varying solubility in different types of solvents.
  • Temperature Dependencies: Like many organic compounds, solubility may increase with temperature. This means that at elevated temperatures, naphthalene-1-carbohydroxamic acid might dissolve better in certain solvents.
  • pH Effects: The solubility can also be impacted by the pH of the solution. In more alkaline or acidic environments, protonation or deprotonation can alter solubility levels significantly.

As a general observation, this compound is expected to be:

  • Moderately soluble in polar solvents such as water and alcohols.
  • Less soluble in nonpolar solvents like hexane due to its hydrophobic character.

Understanding the solubility behavior of naphthalene-1-carbohydroxamic acid is crucial for its applications in various chemical processes, where the dissolution properties can affect reactivity and product formation. To summarize, the solubility profile of naphthalene-1-carbohydroxamic acid is a dynamic interplay of its structural features and environmental conditions, making it a compound of interest for further study in aqueous and organic solution chemistry.

Interesting facts

Interesting Facts About Naphthalene-1-Carbohydroxamic Acid

Naphthalene-1-carbohydroxamic acid is a fascinating chemical compound known for its unique structure and various applications in the field of chemistry. Here are some intriguing insights about this compound:

  • Chemical Structure: The compound features a naphthalene ring, which is a fused bicyclic structure. This aromatic feature contributes to its stability and interesting reactivity.
  • Functional Group: The presence of the hydroxamic acid functional group (-C(=O)N-OH) is significant as it has been widely studied for its biological significance and potential applications as a drug scaffold.
  • Potential Applications:
    • In medicinal chemistry, naphthalene-1-carbohydroxamic acid is explored for its ability to inhibit certain enzymes, possibly making it useful in drug synthesis.
    • It is also investigated in the field of environmental chemistry, where its reactivity could play a role in degrading pollutants.
  • Historical Context: The study of hydroxamic acids dates back over a century, and their synthesis has led to various significant developments in organic chemistry.
  • Research Focus: Current research often emphasizes the compound’s interactions with metal ions, paving the way for investigations in coordination chemistry.

As scientists delve deeper into the exploration of naphthalene-1-carbohydroxamic acid, they continue to uncover its potential and versatility in both theoretical and applied contexts. This compound showcases not just the beauty of chemical structures but also the endless possibilities they offer in scientific innovation.

Synonyms
1-Naphthohydroxamic acid
677-593-3
6953-61-3
N-Hydroxy-1-naphthamide
N-Hydroxynaphthalene-1-carboxamide
HDAC8-IN-2
1-NAPHTHALENECARBOXAMIDE, N-HYDROXY-
NSC 57457
a-Naphthohydroxamic acid
MFCD00059546
CHEMBL115468
NSC-57457
Naphthalene-1-carboxylic acid hydroxyamide
alpha-Naphthohydroxamic acid
BRN 2094470
8GK
naphthylhydroxamic acid
N-Hydroxy-1-naphthamide #
4-09-00-02407 (Beilstein Handbook Reference)
.alpha.-Naphthohydroxamic acid
SCHEMBL2230679
DTXSID30219789
GLXC-07217
KUC110101N
NSC57457
BDBM50015152
AKOS000168064
AS-60201
KSC-229-62-1
1-Naphthohydroxamic Acid, >=98% (HPLC)
DB-019287
HY-130538
CS-0108907
N0023
T72838
HDAC Inhibitor XIX, Compound 2 - CAS 6953-61-3