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Naphthalene-2-carbohydroxamic acid

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Identification
Molecular formula
C11H9NO2
CAS number
22089-28-3
IUPAC name
naphthalene-2-carbohydroxamic acid
State
State

At room temperature, naphthalene-2-carbohydroxamic acid is typically found in a solid state, likely forming a crystalline structure with distinct aromatic properties linked to its naphthalene ring.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.00
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.00
General information
Molecular weight
189.20g/mol
Molar mass
189.1980g/mol
Density
1.2810g/cm3
Appearence

Naphthalene-2-carbohydroxamic acid appears as a solid crystalline compound that might exhibit a white to pale yellow color. Its physical characteristics, such as crystal habit and particle size, can vary based on the method of synthesis or purification.

Comment on solubility

Solubility of Naphthalene-2-carbohydroxamic Acid (C11H9NO2)

Naphthalene-2-carbohydroxamic acid exhibits some intriguing solubility characteristics that are essential for its applications in various chemical processes. Understanding these solubility traits can provide insights into how this compound can be utilized effectively.

Solubility Characteristics

  • Polar vs Nonpolar: Naphthalene-2-carbohydroxamic acid contains both hydrophobic (naphthalene ring) and hydrophilic (carbohydroxamic group) regions, which influences its solubility in different solvents. Typically, it is more soluble in polar solvents due to the presence of functional groups that can engage in hydrogen bonding.
  • Solvent Dependencies: The compound tends to dissolve well in solvents such as water and alcohols, while its solubility in nonpolar solvents is considerably lower. This is primarily due to its ability to form hydrogen bonds in polar environments, making it less favorable for nonpolar surroundings.
  • Temperature Influence: Generally, increasing temperature can enhance solubility, allowing more of the compound to dissolve in a given solvent. However, the extent of this effect can vary depending on the specific solvent used.

In conclusion, the solubility of naphthalene-2-carbohydroxamic acid is significantly influenced by its molecular structure and the nature of the solvent. As a result, when considering this compound for practical applications, it is crucial to factor in these solubility properties for optimal utilization.

Interesting facts

Interesting Facts About Naphthalene-2-Carbohydroxamic Acid

Naphthalene-2-carbohydroxamic acid is a fascinating compound with several noteworthy characteristics and potential applications in various fields. Here are some interesting points to consider:

  • Structural Fascination: This compound features a unique fusion of a hydroxamic acid and a naphthalene ring, contributing to its intriguing structural properties. The presence of the hydroxamic acid functional group makes it particularly interesting for studies related to coordination chemistry.
  • Biological Significance: Hydroxamic acids, including naphthalene-2-carbohydroxamic acid, are known for their biological activity. They can act as inhibitors for metalloproteinases, making them valuable in medicinal chemistry, especially in drug development against various diseases.
  • Industrial Applications: Compounds like naphthalene-2-carbohydroxamic acid may find applications in the development of agrochemicals and pharmaceuticals. Their unique properties can contribute to creating innovative products with specific biological activities.
  • Research Potential: As a compound of interest in ongoing research, naphthalene-2-carbohydroxamic acid could be pivotal in studies involving enzyme inhibition and the development of disease-modifying therapies.
  • Analogous Compounds: Understanding naphthalene-2-carbohydroxamic acid also provides insight into its analogs, allowing scientists to explore variations in structure that may enhance or alter its biological activity.

"The study of compounds like naphthalene-2-carbohydroxamic acid opens new pathways in both chemistry and biochemistry, unlocking secrets that could lead to significant advancements in health and industry."

In summary, naphthalene-2-carbohydroxamic acid is not only a compound of interest for its unique structure but also serves as a gateway to future advancements in science. Its relevance in medicinal chemistry and potential industrial applications make it a noteworthy topic for further exploration.

Synonyms
2-Naphthohydroximic acid
10335-79-2
N-Hydroxy-2-naphthalenecarboxamide
2-Naphthylhydroxamic acid
N,N-Naphthaloylhydroxylamine
N-hydroxynaphthalene-2-carboxamide
2-Naphthalenecarboxamide, N-hydroxy-
2-NAPHTHOHYDROXAMIC ACID
VE8NEC3VME
Naphthalene-2-carboxylic acid hydroxyamide
CHEMBL156672
2-Naphthoylhydroxamic acid
UNII-VE8NEC3VME
SCHEMBL6010034
SCHEMBL8901375
DTXSID70145795
KUC110312N
NAPHTHYLHYDROXAMIC ACID, 2-
BDBM50015160
AKOS000178377
KSC-264-28-1
PD187284