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2-Naphthalenesulfonyl chloride

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Identification
Molecular formula
C10H7ClO2S
CAS number
93-10-7
IUPAC name
naphthalene-2-sulfonyl chloride
State
State
Solid
Melting point (Celsius)
68.00
Melting point (Kelvin)
341.00
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.00
General information
Molecular weight
224.67g/mol
Molar mass
224.6650g/mol
Density
1.4390g/cm3
Appearence

2-Naphthalenesulfonyl chloride appears as a white to light yellow crystalline powder. It possesses a distinctive odor and can be irritating to the skin and eyes. The compound is sensitive to moisture and will degrade when exposed to water.

Comment on solubility

Solubility of Naphthalene-2-sulfonyl Chloride

Naphthalene-2-sulfonyl chloride, commonly abbreviated as NSC, exhibits unique solubility characteristics that are noteworthy for its applications in various chemical reactions and syntheses. Understanding its solubility can provide valuable insights into its behavior and utility in different environments.

Solubility Characteristics

The solubility of naphthalene-2-sulfonyl chloride can be summarized as follows:

  • Polarity: NSC is a polar compound, which influences its solubility characteristics significantly.
  • Solvents: It is generally soluble in organic solvents such as:
    • Ether
    • Acetone
    • Chloroform
  • Insolubility: Its solubility in water is quite limited due to the hydrophobic naphthalene core.

As a result, when using naphthalene-2-sulfonyl chloride, it is crucial to consider the solvent conditions to ensure optimal dissolution. This allows for efficient use in synthesis and reactivity, aligning with the principle that “like dissolves like.” Therefore, it is best utilized in non-aqueous solvent systems to promote better solubility and reactivity.

Interesting facts

Interesting Facts about Naphthalene-2-sulfonyl Chloride

Naphthalene-2-sulfonyl chloride, a significant sulfation agent, plays a vital role in various chemical reactions and applications. Here are some noteworthy points about this compound:

  • Versatile Building Block: It serves as a key intermediate in the synthesis of diverse organic compounds, especially in creating sulfonamide derivatives.
  • Electrophilic Aromatic Substitution: The presence of the sulfonyl group allows for selective electrophilic aromatic substitution reactions, enhancing the reactivity of naphthalene rings.
  • Pharmaceutical Applications: Naphthalene-2-sulfonyl chloride is often utilized in the pharmaceutical industry to develop medications, particularly in synthesizing agents that target bacterial infections.
  • Industrial Use: This compound is instrumental in the production of dyes and pigments, showcasing its potential beyond mere synthesis.
  • Environmental Impact: Due to its aromatic character, researchers are keenly studying the environmental impacts of naphthalene derivatives, considering their persistence and bioaccumulation.

As a chemistry student or a researcher, understanding naphthalene-2-sulfonyl chloride opens up various avenues for exploration, from synthesis methodologies to environmental implications. Its reactivity and applications make it not only a compound of interest but also a tool for innovation in synthetic organic chemistry.

In the words of a prominent chemist, "The beauty of chemistry lies in understanding not just the reactions, but the stories that each compound tells." This certainly rings true for naphthalene-2-sulfonyl chloride, reflecting both its significance and the potential it holds for future discoveries.

Synonyms
2-Naphthalenesulfonyl chloride
Naphthalene-2-sulfonyl chloride
93-11-8
2-Naphthylsulfonyl chloride
beta-Naphthalenesulfonyl chloride
Naphthalene-2-sulfonic acid chloride
beta-Naphthalenesulfochloride
MFCD00004087
.beta.-Naphthalenesulfochloride
2-naphthalenesulphonyl chloride
NAPHTHALENE-2-SULPHONYL CHLORIDE
NSC 133893
2-Naphthalenylsulfonyl chloride
.beta.-Naphthalenesulfonyl chloride
EINECS 202-219-9
beta-Naphthylsulfonyl chloride
naphthalene-2-sulfonylchloride
W3N8WRJ279
2-Naphthalene sulfonyl chloride
.beta.-Naphthylsulfonyl chloride
beta-Naphthalenesulfonyl-chloride
DTXSID5059080
OPECTNGATDYLSS-UHFFFAOYSA-
NSC-133893
2-Naphthalenylsulfonyl Chloride; 2-Naphthylsulfonyl Chloride;NSC 133893; Naphthalene-2-sulfonic Acid Chloridebeta-Naphthalenesulfochloride
ss-Naphthalinsulfochlorid
2-naphtylsulfonyl chloride
2-napthylsulfonyl chloride
2-napthalenesufonylchloride
2-naphtalenesulfonylchloride
2-napthalenesulfonylchloride
2-naphthylsulphonyl chloride
2-Naphthalenesulfonylchloride
2-naphthyl-sulfonyl chloride
UNII-W3N8WRJ279
2-naphtalenesulfonyl chloride
2-Naphthyl sulfonyl chloride
2-napthalenesulfonyl chloride
beta-Naphthalenesulphochloride
SCHEMBL25642
2-naphthalenylsulfonylchloride
2-naphthyl-sulphonyl chloride
2-naphthalene sulfonylchloride
2-naphthalenesulfonyi chloride
beta-Naphthylsulphonyl chloride
2-naphthalene-sulfonyl chloride
2-naphthalene-sulphonyl chloride
DTXCID6048830
beta-Naphthalenesulphonyl chloride
beta-naphthalene-sulphonyl chloride
naphthalin-2-sulfonic acid chloride
naphthaline-2-sulfonic acid chloride
2-Naphthalenesulfonyl chloride, 99%
BBL027447
NSC133893
STL363253
AKOS000118779
CS-W004905
FN07833
VS-0375
DB-057370
N0018
NS00041120
EN300-19464
D77675
A844453
F0808-2035
Z104473932
2-Naphthalenesulfonyl chloride, puriss., >=99.0% (AT)