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Meropenem

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Identification
Molecular formula
C17H25N3O5S
CAS number
96036-03-2
IUPAC name
N,N'-bis[[(1R,4aS)-7-isopropyl-1,4a-dimethyl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methyl]ethane-1,2-diamine;3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State
Meropenem is a solid at room temperature.
Melting point (Celsius)
260.00
Melting point (Kelvin)
533.15
Boiling point (Celsius)
717.10
Boiling point (Kelvin)
990.25
General information
Molecular weight
383.47g/mol
Molar mass
383.4660g/mol
Density
1.3000g/cm3
Appearence
Meropenem is a white to off-white crystalline powder.
Comment on solubility

Solubility of N,N'-bis[[(1R,4aS)-7-isopropyl-1,4a-dimethyl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methyl]ethane-1,2-diamine; 3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The solubility of complex compounds like N,N'-bis[[(1R,4aS)-7-isopropyl-1,4a-dimethyl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methyl]ethane-1,2-diamine; 3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid can depend on several factors:

  • Polarity: Due to the presence of multiple polar functional groups, the compound may exhibit good solubility in polar solvents like water or alcohols.
  • Structure: The *bulky steric hindrance* from the phenanthrene moiety may affect interactions with solvents, potentially decreasing solubility in non-polar solvents.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the amine and carboxylic acid groups may enhance solubility in certain polar solvents.
  • pH Sensitivity: The carboxylic acid group suggests that solubility could be pH-dependent, possibly increasing in basic conditions due to deprotonation.

In summary, while predicting the solubility of such a complex compound requires experimental data, one can generally anticipate a moderate to high solubility in polar solvents influenced by the factors mentioned above. It is essential to conduct in vitro solubility tests to obtain accurate hydrophilicity or lipophilicity metrics.

Interesting facts

Interesting Facts about N,N'-bis[[(1R,4aS)-7-isopropyl-1,4a-dimethyl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methyl]ethane-1,2-diamine;3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This complex compound, with an impressive name, represents an intriguing amalgamation of structural features that contribute to its unique properties and potential applications. Here are some fascinating aspects to consider:

  • Pharmaceutical Potential: Compounds of this nature often find their way into pharmaceutical research. Their complex structures can lead to promising activities against a variety of diseases, showcasing the potential in drug design.
  • Synthetic Chemistry: The synthesis of such elaborate compounds requires advanced techniques in organic chemistry. It provides a rich field for explorations in multi-step synthesis and reaction mechanisms.
  • Biological Significance: The inclusion of thia and azabicyclo structures hints at interesting biological interactions, potentially resulting in bioactive compounds that can modulate biological pathways.
  • Structural Diversity: The combination of isopropyl and phenoxyacetyl groups within the compound highlights the importance of structural diversity in tailoring molecule behavior and function.
  • Research Opportunities: The examination of compounds like this one opens doors for students and researchers alike to explore the fascinating world of organic and medicinal chemistry.

As you delve deeper into the realm of complex organic compounds, remember that each structure holds secrets waiting to be uncovered. Embrace the journey of discovery as you analyze their properties, reactivity, and vast potential in real-world applications!

Synonyms
NS00126599