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Cyclophosphamide

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Identification
Molecular formula
C7H15Cl2N2O2P
CAS number
50-18-0
IUPAC name
N,N-bis(2-chloroethyl)-2-oxo-1,3,2lambda5-oxathiaphospholan-2-amine
State
State
Cyclophosphamide is typically in the solid state at room temperature.
Melting point (Celsius)
50.00
Melting point (Kelvin)
323.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
261.10g/mol
Molar mass
261.0950g/mol
Density
1.3940g/cm3
Appearence

Cyclophosphamide appears as a white crystalline powder. It is known for its high solubility in water, enhancing its practicality for medical applications.

Comment on solubility

Solubility of N,N-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxathiaphospholan-2-amine

The solubility of N,N-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxathiaphospholan-2-amine can vary based on several factors, making it an intriguing compound to study. Understanding its solubility is essential for applications in various fields such as pharmaceuticals and agrochemicals. Here are some key points to consider:

  • Solvent Selection: The compound generally exhibits solubility in polar organic solvents, which may include dimethyl sulfoxide (DMSO) and dimethylformamide (DMF).
  • Temperature Influence: Like many chemical compounds, its solubility can increase with temperature, leading to more favorable interactions with the solvent molecules.
  • pH Sensitivity: The solubility may also be affected by the pH of the solution. Acidic or basic environments can alter the ionization state of the compound, thereby enhancing or diminishing its solubility.

Moreover, it is important to consider that the presence of other solutes can lead to solute-solute interactions, which may complicate solubility assessments. Thus, the statement "solubility is context-dependent" applies well to this compound.

In conclusion, the solubility characteristics of N,N-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxathiaphospholan-2-amine highlight the necessity for thorough experimental evaluation, taking into account the factors mentioned above.

Interesting facts

Exploring N,N-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxathiaphospholan-2-amine

N,N-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxathiaphospholan-2-amine is a fascinating compound that falls within the realm of phosphorothioate chemistry. This compound features a unique oxathiaphospholane structure, which makes it particularly interesting in various applications. Here are some notable aspects to consider:

  • Biologically Active: The presence of the bis(2-chloroethyl) substituents suggests potential **alkylating properties**, which can interact with DNA, making it a candidate for research in **anticancer therapies**.
  • Phosphorus Chemistry: As a phosphorothioate derivative, this compound showcases the versatility of phosphorus in organic synthesis. Compounds containing phosphorus often exhibit unique reactivity under various conditions.
  • Environmental Considerations: Due to its chemical structure, the biodegradation pathways and environmental impact of this compound are areas of ongoing research, especially in the context of potential pollutants.
  • Mechanism of Action: Compounds like this one can act as **prodrugs**, which means they can be biologically activated to exert their therapeutic effects, providing a clever approach to drug design.

This compound represents a crossroad of **pharmaceutical chemistry**, **toxicology**, and **environmental science**. As research continues, further understanding of its properties and potential applications will likely unravel more intriguing details that could aid in developing **targeted therapies**. In the words of a notable chemist, "The beauty of chemistry lies in its ability to transform and innovate – every molecule has a story to tell."

Synonyms
B 833
BRN 2453059
2-(Bis(2-chloroethyl)amino)-1,3,2-oxathiaphospholane 2-oxide
2168-67-4
1,3,2-OXATHIAPHOSPHOLANE, 2-(BIS(2-CHLOROETHYL)AMINO)-, 2-OXIDE
DTXSID10944284
2-[Bis(2-chloroethyl)amino]-1,3,2lambda~5~-oxathiaphospholan-2-one