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Nifuroxazide

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Identification
Molecular formula
C12H9Cl2N3O4
CAS number
965-52-6
IUPAC name
N,N-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enamide
State
State

At room temperature, Nifuroxazide is typically in a solid state, specifically appearing as a crystalline powder.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
314.15g/mol
Molar mass
314.1530g/mol
Density
1.6038g/cm3
Appearence

Nifuroxazide appears as a bright yellow crystalline powder. Its distinct color makes it easily recognizable, and it is commonly used as an intestinal antiseptic agent.

Comment on solubility

Solubility of N,N-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enamide

N,N-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enamide, a complex organic compound, exhibits specific solubility characteristics that are crucial for its applications in various fields. The solubility of this compound can be influenced by several factors:

  • Polarity: Due to the presence of both chloro and nitro groups, the compound is moderately polar, which may enhance its solubility in polar solvents.
  • Solvent Interaction: Common solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF) are expected to solubilize this compound effectively, whereas less polar organic solvents may not.
  • Temperature: Solubility can increase with an increase in temperature, as thermal agitation helps to overcome intermolecular forces.

It is also important to consider the concept of "like dissolves like," meaning:

  1. Non-polar solvents may struggle to solvate this polar compound effectively.
  2. Applications in biological systems or organic synthesis may require specific attention to solvation conditions.

In conclusion, understanding the solubility of N,N-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enamide in various solvents is essential for determining its usability in chemical reactions and biological environments. Further studies may be necessary to quantify its solubility under different conditions to optimize its application potential.

Interesting facts

Exploring N,N-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enamide

N,N-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enamide is an intriguing compound that belongs to the class of amides. This compound has garnered attention for its diverse applications and interesting structural characteristics.

Key Features:

  • Biological Activity: The presence of the nitro group and the furan ring suggests potential bioactivity. Compounds with such structures often exhibit antimicrobial and anticancer properties, making them a subject of interest in medicinal chemistry.
  • Synthesis: This compound can be synthesized using methods involving nucleophilic substitution, which is a common practice for creating chloroethyl derivatives. Such synthetic routes could be optimized to enhance yield and purity.
  • Reactivity: The chloromethyl groups are known to engage in further reactions, which can lead to a variety of derivatives. This reactivity is essential for the development of new pharmacologically relevant compounds.
  • Applications: Beyond its potential therapeutic uses, its unique chemical structure allows it to act as a versatile building block in organic synthesis, paving the way for further chemical innovation.

By understanding the structure and function of N,N-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enamide, chemists can leverage its properties for advancements in drug development and synthetic chemistry. As noted in the field, "chemistry is a journey through the landscape of molecules," and compounds like this are definitely part of that exciting trek!

With ongoing research, this compound could potentially play a pivotal role in the development of new therapeutic agents, making it a noteworthy topic for further exploration in both academic and industrial contexts.