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Nifuroxazide

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Identification
Molecular formula
C12H12Cl2N4O5
CAS number
965-52-6
IUPAC name
N',N'-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enehydrazide
State
State

At room temperature, Nifuroxazide is in a solid state, presented as a powder. Being a nitrofuran derivative, it remains stable when stored properly in its solid form without exposure to excessive moisture or light.

Melting point (Celsius)
216.00
Melting point (Kelvin)
489.15
Boiling point (Celsius)
482.10
Boiling point (Kelvin)
755.25
General information
Molecular weight
275.13g/mol
Molar mass
275.1300g/mol
Density
1.6867g/cm3
Appearence

Nifuroxazide is typically a yellow crystalline powder. This powder is almost insoluble in water and is stable under normal temperatures and pressures. Its color can be attributed to the nitrofuran group in the compound, which often imparts a yellow hue to such substances.

Comment on solubility

Solubility of N',N'-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enehydrazide

The solubility of N',N'-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enehydrazide can be intriguing due to its complex structure. Generally, the solubility of organic compounds such as this one can be influenced by several factors, including:

  • Polarity: The presence of polar functional groups, such as the nitro group, often enhances solubility in polar solvents.
  • Hydrophobic regions: The chloroethyl groups contribute hydrophobic characteristics, which may lead to limited solubility in highly polar solvents.
  • Temperature: As with many compounds, solubility can increase with temperature; thus, heating may help dissolve the compound better.
  • Solvent choice: Different solvents will yield varying solubility results; water, ethanol, or organic solvents like DMSO might show different outcomes.

In summary, while N',N'-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enehydrazide may exhibit moderate solubility in some organic solvents, its solubility profile would likely necessitate specific conditions or solvent systems for effective dissolution. As always, laboratory testing is essential to accurately determine the solubility characteristics of this intriguing compound.

Interesting facts

Interesting Facts about N',N'-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enehydrazide

N',N'-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enehydrazide is a fascinating compound that has marked significance in both the fields of medicinal chemistry and agricultural science. Here are some intriguing highlights:

  • Chemical Structure: This compound features unique functional groups that contribute to its reactivity and potential applications. The presence of both chloroethyl and nitrofuran moieties enhances the compound's biological activity.
  • Biological Activity: It has been studied for its potential as an anti-cancer agent. Research indicates it may interfere with the growth of specific cancer cells, making it a promising candidate for oncology therapies.
  • Agricultural Applications: Compounds with similar structures have been considered for use as herbicides or pesticides, showcasing the dual utility of such chemical entities in both healthcare and agriculture.
  • Mechanism of Action: The compound's ability to form reactive intermediates may allow it to engage various biological targets, providing insight into how certain treatments could be developed.
  • Historical Context: The study of hydrazides has led to numerous discoveries in pharmacology, with many derivatives being explored for their therapeutic properties. This compound exemplifies the innovation derived from modifying known structures to enhance efficacy.
  • Safety and Environmental Impact: As with many synthetic compounds, understanding the safety profile and environmental impact is critical. Research is ongoing to assess any potential risks associated with its use in agricultural applications.

In summary, N',N'-bis(2-chloroethyl)-3-(5-nitro-2-furyl)prop-2-enehydrazide represents a compound at the intersection of several fields, offering opportunities for advancements in both medicinal chemistry and agricultural science. Its complex structure and varied applications make it a compelling subject for further study and exploration.