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Dacarbazine

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Identification
Molecular formula
C11H18Cl2N2O2
CAS number
4342-03-4
IUPAC name
N,N-bis(2-chloroethyl)-4-(1,3-dioxan-2-yl)aniline
State
State

At room temperature, Dacarbazine is typically a solid.

Melting point (Celsius)
185.50
Melting point (Kelvin)
458.60
Boiling point (Celsius)
482.64
Boiling point (Kelvin)
755.79
General information
Molecular weight
364.18g/mol
Molar mass
364.2770g/mol
Density
1.1620g/cm3
Appearence

Dacarbazine is a white to pale yellow crystalline solid.

Comment on solubility

Solubility of N,N-bis(2-chloroethyl)-4-(1,3-dioxan-2-yl)aniline

N,N-bis(2-chloroethyl)-4-(1,3-dioxan-2-yl)aniline, with the chemical formula C11H18Cl2N2O2, presents interesting solubility characteristics that are influenced by its unique structure. Understanding the solubility of this compound is essential for predicting its behavior in different environments.

Key factors affecting its solubility include:

  • Polarity: The presence of the dioxane moiety may increase the overall polarity of the compound, potentially enhancing solubility in polar solvents.
  • Chlorine Atoms: The chlorinated groups may also contribute to the solubility profile; chlorinated compounds often have varying solubility in organic solvents.
  • Hydrogen Bonding: Potential hydrogen bonding interactions, particularly with water or other polar solvents, could influence how well this compound dissolves in those media.
  • Concentration Effects: As with many organic compounds, solubility may also be concentration-dependent, meaning that saturation levels can affect its overall solubility.

While the solubility profile of N,N-bis(2-chloroethyl)-4-(1,3-dioxan-2-yl)aniline is not extensively documented, it is crucial to consider these factors when assessing its practical applications, especially in chemical formulations or biological systems.

In summary, this compound's solubility is contingent upon its molecular structure and interactions with various solvents, and further studies may be necessary to determine precise solubility limits.

Interesting facts

Interesting Facts about N,N-bis(2-chloroethyl)-4-(1,3-dioxan-2-yl)aniline

N,N-bis(2-chloroethyl)-4-(1,3-dioxan-2-yl)aniline is a unique compound with intriguing chemical and practical applications. Here are some fascinating aspects of this compound:

  • Dual Functionality: This compound features both a chloroethyl group and a dioxane ring, making it versatile for various chemical reactions. The chloroethyl groups can participate in nucleophilic substitution reactions, while the dioxane moiety often enhances solubility and stability.
  • Pharmaceutical Interest: Compounds like N,N-bis(2-chloroethyl)-4-(1,3-dioxan-2-yl)aniline may exhibit potential as intermediates in the synthesis of pharmaceuticals due to their unique structure. The presence of the aniline moiety provides sites for further chemical modifications, which can lead to the creation of novel therapeutic agents.
  • Environmental Considerations: Given the chlorine atoms in its structure, understanding the environmental behavior and degradation pathways of this compound is essential. Chlorinated compounds can have significant ecological impacts, thus necessitating thorough studies on their toxicity and bioaccumulation.
  • Safety Measures: When handling N,N-bis(2-chloroethyl)-4-(1,3-dioxan-2-yl)aniline, it's important to implement strict safety protocols. The presence of halogens suggests caution due to potential reactivity and toxicity.

As a compound of interest in both synthetic chemistry and material science, N,N-bis(2-chloroethyl)-4-(1,3-dioxan-2-yl)aniline continues to inspire research and application innovations.

"Exploring the depths of chemical compounds often reveals more than just their structure; it exposes the potential for new discoveries."

Synonyms
m-DIOXANE, 2-(p-BIS(2-(CHLOROETHYL)AMINO)PHENYL)-
10549-94-7
NSC 100418
BRN 1385532
2-(p-Bis(2-(chloroethyl)amino)phenyl)-m-dioxane
Benzaldehyde nitrogen mustard trimethylene glycol acetal
DTXSID10147157
5-19-08-00412 (Beilstein Handbook Reference)
DTXCID8069648
N,N-bis(2-chloroethyl)-4-(1,3-dioxan-2-yl)aniline
NSC100418
NSC-100418