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4-Fluorophenylbis(2-chloroethyl)amine

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Identification
Molecular formula
C10H12Cl2FN
CAS number
785-84-4
IUPAC name
N,N-bis(2-chloroethyl)-4-fluoro-aniline
State
State

At room temperature, N,N-bis(2-chloroethyl)-4-fluoro-aniline is typically in a liquid state.

Melting point (Celsius)
-23.00
Melting point (Kelvin)
250.15
Boiling point (Celsius)
141.00
Boiling point (Kelvin)
414.15
General information
Molecular weight
221.11g/mol
Molar mass
221.1100g/mol
Density
1.2743g/cm3
Appearence

N,N-bis(2-chloroethyl)-4-fluoro-aniline typically appears as a colorless to pale yellow liquid. It may have a slight aromatic odor.

Comment on solubility

Solubility of N,N-bis(2-chloroethyl)-4-fluoro-aniline

N,N-bis(2-chloroethyl)-4-fluoro-aniline is an intriguing compound when it comes to its solubility characteristics. The solubility of this compound can be influenced by several factors, including its structural features and the nature of the solvent used. Here are some key points to consider:

  • Polarity: The presence of the 2-chloroethyl groups and the fluoro substituent contribute to the overall polarity of the compound, affecting its interaction with polar solvents like water.
  • Hydrophobic vs Hydrophilic: Given the alkyl and chlorinated groups, the compound exhibits a degree of hydrophobicity, which could limit its solubility in aqueous solutions.
  • Common Solvents: It is likely to be more soluble in organic solvents such as dimethyl sulfoxide (DMSO), dimethylformamide (DMF), or ethanol compared to water.
  • Temperature Dependence: Like many organic compounds, solubility may increase with temperature, suggesting that heating the solvent could enhance solubility.

In summary, while N,N-bis(2-chloroethyl)-4-fluoro-aniline is expected to show limited solubility in water, its solubility in organic solvents could be more favorable. Understanding these solubility dynamics is crucial for practical applications and industrial processes.

Interesting facts

Interesting Facts about N,N-bis(2-chloroethyl)-4-fluoro-aniline

N,N-bis(2-chloroethyl)-4-fluoro-aniline is a fascinating compound that has intrigued scientists due to its unique structure and potential applications. Here are some notable aspects:

  • Structure Highlights: This compound possesses both chlorine and fluorine substituents, which can significantly influence its reactivity and stability. The presence of the amine group further adds to its chemical properties.
  • Biological Activity: Compounds containing the 4-fluoro-aniline moiety are often investigated for their biological activities, including potential roles in pharmaceuticals. The unique combination of functional groups in N,N-bis(2-chloroethyl)-4-fluoro-aniline may contribute to its interactions with biological systems.
  • Industrial Relevance: This compound can serve as an intermediate in the synthesis of various agrochemicals and pharmaceuticals. The ability to modify its structure allows researchers to tailor compounds for specific types of chemical reactions.
  • Environmental Implications: With the introduction of chlorinated compounds, understanding their environmental impact is crucial. Chemists are continually studying how such compounds behave in different ecosystems, influencing safety protocols and regulations.

In summary, N,N-bis(2-chloroethyl)-4-fluoro-aniline is not just a compound of chemical interest but also plays a role in the broader context of environmental safety and pharmaceutical development. Its complex interactions inspire further research and discovery in the field of chemistry.

Synonyms
22116-18-3
THX7B4FV58
N,N-Bis(2-chloroethyl)-p-fluoroaniline
ANILINE, N,N-BIS(2-CHLOROETHYL)-p-FLUORO-
NSC 269048
NSC-269048
BRN 2838457
DTXSID00176633
N,N-BIS(2-CHLOROETHYL)-4-FLUOROBENZENAMINE
RefChem:199597
DTXCID8099124
Benzenamine, N,N-bis(2-chloroethyl)-4-fluoro-
NSC269048
UNII-THX7B4FV58
SCHEMBL5987618
WHBKJPHTKQXBNJ-UHFFFAOYSA-N
N,N-di(2-chloroethyl)-4-fluoroaniline
N,N-bis(2-chloroethyl)-4-fluorophenylamine
Benzenamine,N-bis(2-chloroethyl)-4-fluoro-