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Identification
Molecular formula
C18H20Cl2NO
CAS number
15301-48-5
IUPAC name
N,N-bis(2-chloroethyl)-4-methoxy-3-methyl-naphthalen-1-amine
State
State

This compound is in a crystalline solid state at room temperature.

Melting point (Celsius)
70.00
Melting point (Kelvin)
343.15
Boiling point (Celsius)
383.00
Boiling point (Kelvin)
656.15
General information
Molecular weight
325.55g/mol
Molar mass
325.5530g/mol
Density
1.3000g/cm3
Appearence

N,N-bis(2-chloroethyl)-4-methoxy-3-methyl-naphthalen-1-amine is typically observed as a crystalline solid with a yellowish tint.

Comment on solubility

Solubility of N,N-bis(2-chloroethyl)-4-methoxy-3-methyl-naphthalen-1-amine

The solubility of N,N-bis(2-chloroethyl)-4-methoxy-3-methyl-naphthalen-1-amine can be influenced by several factors, including its molecular structure and the presence of functional groups. Here are some key points regarding its solubility:

  • Polarity: The chlorinated ethyl groups and the methoxy group contribute to the compound's overall polarity, which can enhance interactions with polar solvents like water.
  • Functional Groups: The presence of methoxy (-OCH₃) and chloro (-Cl) groups typically suggests that the compound may have moderate solubility in organic solvents, while its solubility in water could be limited.
  • Solvent Influence: The solubility may vary significantly in different solvents:
    • Readily soluble: in non-polar solvents such as hexane and dichloromethane.
    • Limited solubility: in polar solvents, including water and alcohols.

Understanding these factors is crucial for applications involving this compound, as solubility plays a pivotal role in its behavior in various chemical reactions and formulations.

Interesting facts

Interesting Facts about N,N-bis(2-chloroethyl)-4-methoxy-3-methyl-naphthalen-1-amine

N,N-bis(2-chloroethyl)-4-methoxy-3-methyl-naphthalen-1-amine, commonly recognized in the field for its complex structure and unique properties, serves an important role in various scientific applications. Here are some intriguing aspects of this compound:

  • Versatile Applications: This compound is utilized in medicinal chemistry and has been studied for its potential pharmacological properties, particularly as an antitumor agent.
  • Structural Features: The presence of the naphthalene moiety contributes to the compound's aromatic character, which can influence its reactivity and interactions with biological systems.
  • Mechanistic Insights: Research indicates that compounds like this one may act through mechanisms involving DNA alkylation, thereby disrupting cellular processes in specific types of cancer cells.
  • Synthetic Pathways: The synthesis of this compound involves multiple steps, typically starting from precursors with naphthalene structures and incorporating chloroethyl groups through complex organic transformations.
  • Potential Side Effects: As with many such compounds, there are ongoing studies examining the dose-dependent toxicity and side effects as they relate to both therapeutic and adverse outcomes.

Furthermore, the adaptability of this compound in **chemical synthesis** makes it a focal point of ongoing research. Scientists often quote that "understanding the intricate design of such compounds is crucial in drug development." As the field of medicinal chemistry advances, compounds like N,N-bis(2-chloroethyl)-4-methoxy-3-methyl-naphthalen-1-amine will continue to illuminate pathways to novel treatments and therapies.

Synonyms
Mitoclomine
17692-54-5
Mitoclomina
NSC-114575
Mitoclominum
N,N-bis(2-Chloroethyl)-4-methoxy-3-methyl-1-naphthylamine
02DQX562CR
DTXSID30170220
NSC114575
DTXCID3092711
N,N-Bis(2-chloroethyl)-4-methoxy-3-methyl-1-naphthalenamine
N,N-bis(2-chloroethyl)4-amino-2-methyl-1-methoxy-naphthalene
241-687-9
N,N-bis(2-chloroethyl)-4-methoxy-3-methylnaphthalen-1-amine
NSC 114575
WBA 7707
Mitoclomina [INN-Spanish]
Mitoclomine [INN:BAN]
1-Naphthalenamine, N,N-bis(2-chloroethyl)-4-methoxy-3-methyl- (9CI)
Mitoclominum [INN-Latin]
EINECS 241-687-9
BRN 2943587
UNII-02DQX562CR
N,N-Di-(2-chloroethyl)-4-methoxy-3-methyl-1-naphthylamine
1-Naphthalenamine, N,N-bis(2-chloroethyl)-4-methoxy-3-methyl-
MITOCLOMINE [INN]
1-NAPHTHYLAMINE, N,N-BIS(2-CHLOROETHYL)-4-METHOXY-3-METHYL-
orb1696088
SCHEMBL2109906
CHEMBL2106926
SCHEMBL30388025
CLZXREZAEIUCGG-UHFFFAOYSA-N
AKOS022181455
SB83217
DB-361182
NS00025823
Q27231519
1-Naphthylamine,N-bis(2-chloroethyl)-4-methoxy-3-methyl-
1-Naphthalenamine,N-bis(2-chloroethyl)-4-methoxy-3-methyl-