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Nitrofurazone

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Identification
Molecular formula
C6H6Cl2N4O4
CAS number
59-87-0
IUPAC name
N,N-bis(2-chloroethyl)-5-nitro-furan-2-carboxamide
State
State

Solid at room temperature. It is stable and does not vaporize easily, maintaining its solid form under standard conditions.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
-1.00
Boiling point (Kelvin)
-1.00
General information
Molecular weight
198.15g/mol
Molar mass
198.1460g/mol
Density
1.6500g/cm3
Appearence

Nitrofurazone appears as a bright yellow, crystalline solid. It is often found as a powder and is known for its vivid color.

Comment on solubility

Solubility of N,N-bis(2-chloroethyl)-5-nitro-furan-2-carboxamide

N,N-bis(2-chloroethyl)-5-nitro-furan-2-carboxamide is a compound that presents interesting solubility characteristics. Its solubility can be significantly influenced by several factors:

  • Polarity: The presence of a nitro group (-NO2) and a carboxamide group (-CONH2) contributes to the overall polarity of the molecule, which can enhance its solubility in polar solvents.
  • Solvent Interaction: This compound is more likely to dissolve in solvents such as water and alcohols due to hydrogen bonding capability. Conversely, it may exhibit limited solubility in non-polar solvents.
  • Temperature Effects: As with many chemical compounds, temperature changes can affect solubility. Typically, an increase in temperature may lead to an increased solubility of solid compounds in liquids.
  • pH Influence: The solubility might also shift according to the pH of the solution, particularly due to the acidic nature of the carboxamide group.

In summary, the solubility of N,N-bis(2-chloroethyl)-5-nitro-furan-2-carboxamide reflects its complex chemical structure, making it an intriguing subject for further exploration. As the saying goes, “Like dissolves like,” so understanding the molecular interactions is key to predicting its behavior in various environments.

Interesting facts

Interesting Facts about N,N-bis(2-chloroethyl)-5-nitro-furan-2-carboxamide

N,N-bis(2-chloroethyl)-5-nitro-furan-2-carboxamide is a compound that showcases the fascinating intersection of medicinal chemistry and agricultural applications. This compound is essential for its unique structural features and biological relevance. Here are some intriguing points about this compound:

  • Biological Activity: It has been studied for its potential as an anticancer agent, exhibiting cytotoxic properties that can disrupt the proliferation of cancer cells.
  • Pesticide Potential: This compound's design suggests it may also serve as a pesticide, with capabilities to target specific pests while minimizing harm to beneficial organisms.
  • Mechanism of Action: The presence of the nitro group and the chloroethyl side chains contributes to its reactivity, making it an interesting candidate for designing new therapeutic agents.
  • Structure-Activity Relationship (SAR): Its unique furan ring structure allows scientists to modify and analyze the compound in efforts to enhance its efficacy and reduce side effects.
  • Environmental Considerations: Research into the environmental impact of such compounds is crucial, particularly regarding their degradation products and potential bioaccumulation.

In summary, N,N-bis(2-chloroethyl)-5-nitro-furan-2-carboxamide illustrates the intricate balance between chemistry, biology, and environmental science. As research continues, compounds like this one could lead to significant advancements in both medicine and agriculture, highlighting the ever-valuable role of chemistry in tackling real-world challenges.

Synonyms
2-FURAMIDE, N,N-BIS(2-CHLOROETHYL)-5-NITRO-
BRN 1389095
N,N-Bis(2-chloroethyl)-5-nitro-2-furamide
1901-10-6
DTXSID40172477
DTXCID8094968
N,N-bis(2-chloroethyl)-5-nitrofuran-2-carboxamide