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Nitrogen Mustard FC

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Identification
Molecular formula
C9H11Cl2NO2
CAS number
130471-99-9
IUPAC name
N,N-bis(2-chloroethyl)furan-2-carboxamide
State
State

At room temperature, Nitrogen Mustard FC is typically found as a crystalline solid. Under specific conditions, especially with changes in temperature and pressure, it can also transition into other states to accommodate various storage and application needs.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.10
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.20
General information
Molecular weight
236.10g/mol
Molar mass
236.1280g/mol
Density
1.3650g/cm3
Appearence

Nitrogen Mustard FC is typically an off-white to pale yellow crystalline solid. The compound is known for its mustard-like odor, which is often associated with chloroalkylamine derivatives and related furan carboxamides.

Comment on solubility

Solubility of N,N-bis(2-chloroethyl)furan-2-carboxamide

N,N-bis(2-chloroethyl)furan-2-carboxamide is a compound that showcases unique solubility characteristics. Understanding its solubility is crucial, particularly in applications such as pharmaceuticals and chemical synthesis.

Key Insights on Solubility:

  • Solvent Interaction: The solubility of this compound can be largely influenced by the solvent used. Generally, it displays greater solubility in polar organic solvents.
  • Hydrophobic and Hydrophilic Features: The presence of the furan ring suggests some level of hydrophobicity, while the chloroethyl groups introduce polar characteristics. This dual nature affects how the compound interacts with various solvents.
  • Concentration Dependency: As common in many compounds, its solubility can vary with concentration; higher concentrations may lead to decreased solubility due to intermolecular interactions.

Understanding these aspects allows researchers to manipulate conditions for optimal results. As noted, "the solubility properties of a compound are pivotal in determining its behavior in chemical reactions and biological interactions." Thus, N,N-bis(2-chloroethyl)furan-2-carboxamide must be tested under varying conditions to ascertain its precise solubility profile.

Interesting facts

Interesting Facts About N,N-bis(2-chloroethyl)furan-2-carboxamide

N,N-bis(2-chloroethyl)furan-2-carboxamide is a fascinating compound with significant relevance in the fields of organic chemistry and medicinal chemistry. Here are some compelling aspects of this chemical:

  • Chemical Structure: This compound features a unique furan ring, which contributes to its chemical reactivity and potential applications. The presence of chloroethyl groups enhances its electrophilic properties.
  • Applications in Medicine: Compounds with similar structures are often studied as potential drug candidates. Their ability to interact with biological targets makes them of interest in pharmacology, particularly in the development of anticancer therapies.
  • Mechanism of Action: The 2-chloroethyl moiety is known to participate in alkylation reactions. This can lead to DNA cross-linking, disrupting replication in rapidly dividing cells, which is a mechanism utilized in some chemotherapeutic agents.
  • Research Significance: Researchers are continually investigating derivatives of furan-based compounds, as they may possess antimicrobial, anti-inflammatory, and antitumor activities. This particular compound serves as a model for understanding these interactions.
  • Safety and Handling: As with many chlorinated compounds, safety considerations are paramount. Proper safety protocols must be followed, as they can be hazardous if mishandled.

In summary, N,N-bis(2-chloroethyl)furan-2-carboxamide is not merely a chemical entity; it exemplifies the intricate relationship between structure and function in medicinal chemistry. Understanding compounds like this is crucial for advancing therapeutic strategies in modern healthcare.

Synonyms
2-FURAMIDE, N,N-BIS(2-CHLOROETHYL)-
BRN 1370077
1901-08-2
N,N-Bis(2-chloroethyl)-2-furamide
DTXSID80172476
DTXCID3094967
N,N-bis(2-chloroethyl)furan-2-carboxamide