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Symclosene

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Identification
Molecular formula
C18H20Cl2N2
CAS number
51221-10-0
IUPAC name
N,N'-bis[(2-chlorophenyl)methyl]ethane-1,2-diamine
State
State

At room temperature, N,N'-bis[(2-chlorophenyl)methyl]ethane-1,2-diamine is a solid substance, appearing as crystalline powder.

Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
324.06g/mol
Molar mass
324.0610g/mol
Density
1.0690g/cm3
Appearence
This compound appears as a white crystalline powder.
Comment on solubility

Solubility of N,N'-bis[(2-chlorophenyl)methyl]ethane-1,2-diamine

The solubility of N,N'-bis[(2-chlorophenyl)methyl]ethane-1,2-diamine can be categorized based on several factors:

  • Polar vs. Nonpolar Solvents: This compound, with its multiple aromatic rings, may exhibit limited solubility in polar solvents like water but can dissolve more readily in nonpolar organic solvents.
  • Temperature Dependency: As with many organic compounds, solubility can increase with temperature, allowing for better dissolution in solvents at higher temperatures.
  • Concentration Effects: In a diluted solution, solubility will vary; maximum saturation points depend on the solvent used and the presence of other solutes.
  • Functional Groups: The presence of amino groups (-NH2) indicates potential interactions with solvents, but the bulky chlorophenyl groups may hinder solvation.

In summary, while N,N'-bis[(2-chlorophenyl)methyl]ethane-1,2-diamine may not be highly soluble in water, it can still be effectively dissolved in nonpolar organic solvents under optimal conditions. As noted, “solubility is a key factor in determining the utility of compounds in various applications,” making it an essential consideration in chemical use and formulation.

Interesting facts

Interesting Facts about N,N'-bis[(2-chlorophenyl)methyl]ethane-1,2-diamine

N,N'-bis[(2-chlorophenyl)methyl]ethane-1,2-diamine is a fascinating compound with significant implications in various fields of research and application. Here are some captivating points about this compound:

  • Chemical Structure: This compound features an intriguing structure that includes two 2-chlorophenyl groups connected by an ethylene bridge, which plays a vital role in its reactivity and binding affinity to biological targets.
  • Biological Activity: The compound is noted for its potential therapeutic applications. Many compounds with similar structural motifs are studied for their ability to interact with specific biological receptors, making them interesting candidates in medicinal chemistry.
  • Research Interest: Researchers are exploring the effects of halogen substituted aromatic groups, such as chlorophenyl, on the pharmacological properties of drugs. This compound's unique configuration could lead to the development of new drugs that target specific diseases.
  • Applications in Material Science: Compounds with amine functionalities, like this one, can be utilized in creating advanced materials, especially in areas where polymers and coatings play a critical role in product performance.
  • Synthesis Route: The synthetic pathways to obtain such compounds can be complex and often involve multi-step reactions. Studying synthetic methods enhances the understanding of reaction mechanisms and can lead to the discovery of innovative methodologies in organic chemistry.
  • Toxicology and Safety: Compounds incorporating chlorine atoms often raise concerns regarding their environmental stability and biological effects. Thus, studies on this compound should also consider potential toxicity and ecotoxicological profiles.

In summary, N,N'-bis[(2-chlorophenyl)methyl]ethane-1,2-diamine stands at the intersection of chemistry and pharmacology, offering promising avenues for both research and practical applications. Its unique structure and potential versatility make it a compound worth exploring further.

Synonyms
n,n'-bis(2-chlorobenzyl)ethane-1,2-diamine
108896-78-2
N,N'-bis[(2-chlorophenyl)methyl]ethane-1,2-diamine
Ticlopidine Impurity J
UNII-FBE37K4O5V
FBE37K4O5V
N,N'-Bis(o-chlorobenzyl)ethylenediamine
Ticlopidine hydrochloride impurity J [EP]
1,2-Ethanediamine, N1,N2-bis((2-chlorophenyl)methyl)-
DTXSID501225088
N1,N2-Bis[(2-chlorophenyl)methyl]-1,2-ethanediamine
Q27277906
TICLOPIDINE HYDROCHLORIDE IMPURITY J [EP IMPURITY]