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N,N-bis(2-iodoethyl)aniline

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Identification
Molecular formula
C10H13IN2
CAS number
40520-70-5
IUPAC name
N,N-bis(2-iodoethyl)aniline
State
State

At room temperature, N,N-bis(2-iodoethyl)aniline is in a liquid state. It is stable under normal conditions but should be stored in a dry, cool place away from light and air to prevent degradation.

Melting point (Celsius)
5.00
Melting point (Kelvin)
278.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
387.03g/mol
Molar mass
387.0260g/mol
Density
2.1680g/cm3
Appearence

N,N-bis(2-iodoethyl)aniline is typically a colorless to pale yellow liquid. It is known for its characteristic odor and moderate viscosity. The compound is sensitive to light and air, which might lead to discoloration over time.

Comment on solubility

Solubility of N,N-bis(2-iodoethyl)aniline

N,N-bis(2-iodoethyl)aniline, with a chemical formula that reflects its complex structure, exhibits intriguing solubility characteristics. Understanding its solubility can be crucial for applications in various fields, including pharmaceuticals and material science. Here are some key considerations:

  • Polar vs. Non-Polar: The presence of the iodine atoms in its structure contributes to both polar and non-polar characteristics, which can affect solubility in different solvents.
  • Solvent Compatibility: Typically, compounds with significant iodine content are more soluble in organic solvents such as chloroform, ether, or dimethyl sulfoxide (DMSO), rather than in polar solvents like water.
  • Temperature Influences: As with many chemical compounds, solubility can increase with temperature. Thus, heating the solvent may help dissolve N,N-bis(2-iodoethyl)aniline more effectively.
  • Concentration Dependency: At higher concentrations, saturation may be reached quickly, leading to decreased solubility, which could be a factor in experimental settings.

In summary, while N,N-bis(2-iodoethyl)aniline may not demonstrate high solubility in aqueous solutions, it shows promising solubility in organic solvents, influenced by temperature and concentration. This dual characteristic makes it a versatile compound for various applications.

Interesting facts

Interesting Facts about N,N-bis(2-iodoethyl)aniline

N,N-bis(2-iodoethyl)aniline is a fascinating compound with a variety of applications in both research and industrial settings. Its unique structure and properties make it an intriguing subject for chemists and students alike. Here are some interesting facts:

  • Structure and Functionality: This compound features a central aniline moiety, which is a benzene ring bonded to an amino group, that is further substituted with two 2-iodoethyl groups. The presence of iodine atoms enhances its reactivity, making it particularly useful for further synthetic transformations.
  • Reactivity: The iodine atoms in the molecule can participate in nucleophilic substitution reactions, allowing for the synthesis of a wide range of derivatives. This characteristic is essential in fields such as medicinal chemistry and materials science.
  • Role in Drug Discovery: Compounds like N,N-bis(2-iodoethyl)aniline can serve as key intermediates in the development of pharmaceutical agents. The iodoethyl groups may be involved in targeting specific biological pathways, thus playing a potential role in drug design.
  • Potential as a Research Tool: In chemical studies, this compound can be employed as a reagent for labeling molecules with iodine isotopes. This property is especially valuable in tracer studies and other areas of biochemical research.
  • Safety Considerations: As with many organoiodine compounds, proper handling and safety precautions are vital due to the potential toxicity of iodine and its derivatives. Understanding the hazards associated with this compound is crucial for safe laboratory practices.

In summary, N,N-bis(2-iodoethyl)aniline stands out due to its versatile applications in synthesis and research, making it a valuable compound in organic chemistry. Its distinctive structure not only adds to its chemical reactivity but also enhances its potential in various industrial and medicinal fields.

Synonyms
N,N-Bis(2-iodoethyl)aniline
ANILINE, N,N-BIS(2-IODOETHYL)-
29523-51-1
BRN 2804899
DTXSID90183710
3-12-00-00264 (Beilstein Handbook Reference)
RefChem:319631
DTXCID30106201
N,N-bis-(2-iodoethyl)aniline
CHEMBL283163
SCHEMBL20644247