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N,N'-bis(4-chlorophenyl)acetamidine

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Identification
Molecular formula
C14H12Cl2N2
CAS number
728-88-1
IUPAC name
N,N'-bis(4-chlorophenyl)acetamidine
State
State

At room temperature, N,N'-bis(4-chlorophenyl)acetamidine is in a solid state, specifically a crystalline solid.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.00
Boiling point (Celsius)
520.00
Boiling point (Kelvin)
793.00
General information
Molecular weight
282.17g/mol
Molar mass
282.1690g/mol
Density
1.3400g/cm3
Appearence

N,N'-bis(4-chlorophenyl)acetamidine appears as a crystalline solid with a light yellow to off-white color. The appearance may vary depending on the purity and sample size. It typically forms well-defined crystal structures.

Comment on solubility

Solubility of N,N'-bis(4-chlorophenyl)acetamidine

N,N'-bis(4-chlorophenyl)acetamidine is a chemical compound that exhibits interesting solubility characteristics. Understanding its solubility is essential for applications in both research and industrial contexts.

When discussing the solubility of this compound, several key factors come into play:

  • Polar vs. Non-Polar Solvents: Due to its amidine functional group, N,N'-bis(4-chlorophenyl)acetamidine generally demonstrates a preference for polar solvents.
  • Temperature Influence: The solubility may increase with temperature, which is a common trend for many organic compounds.
  • Crystal Structure: The degree of crystallinity can influence solubility, with more amorphous forms tending to be more soluble than their crystalline counterparts.
  • pH Sensitivity: The solubility in aqueous solutions can vary depending on the pH, due to potential protonation of the amine group, enhancing its solubility.

As summarized by the classic principle of solubility:

"Like dissolves like."

Thus, N,N'-bis(4-chlorophenyl)acetamidine will generally be more soluble in solvents that have similar polar characteristics. This aspect makes it crucial to select the right solvent in experimental conditions to maximize its potential applications.

Interesting facts

Interesting Facts about N,N'-bis(4-chlorophenyl)acetamidine

N,N'-bis(4-chlorophenyl)acetamidine is a fascinating compound with various applications in the field of chemistry and medicine. Here are some intriguing aspects:

  • Structure and Bonding: This compound features an amidine functional group, which contributes to its unique reactivity and properties. Its structure is characterized by the presence of two 4-chlorophenyl groups, which enhances its stability and solubility in various solvents.
  • Biological Activity: Research indicates that N,N'-bis(4-chlorophenyl)acetamidine exhibits noteworthy biological activities, making it a subject of interest in medicinal chemistry. Some studies have suggested it may possess antimicrobial and anti-inflammatory properties.
  • Applications in Organometallic Chemistry: This compound can act as a ligand in organometallic complexes, facilitating various catalytic reactions. As a ligand, it enhances the reactivity and selectivity of metal complexes in synthetic processes.
  • Research Potential: There is ongoing research into this compound for its potential in developing new pharmaceutical agents. The structural attributes enable various modifications, allowing scientists to design derivatives with enhanced efficacy.
  • Synthesis: The synthesis of N,N'-bis(4-chlorophenyl)acetamidine often involves the reaction of 4-chlorobenzoyl chloride with ammonia derivatives, showcasing fundamental organic transformation techniques in laboratories.

In conclusion, N,N'-bis(4-chlorophenyl)acetamidine stands out not only for its unique chemical structure but also for its wide-ranging potential in research and applications. As chemists continue to explore its properties, this compound may uncover new dimensions in both chemistry and medicinal science.

Synonyms
ACETAMIDINE, N,N'-BIS(p-CHLOROPHENYL)-
N,N'-Bis(p-chlorophenyl)acetamidine
Ethanimidamide, N,N'-bis(4-chlorophenyl)-
NSC 194853
DTXSID90176900
RefChem:315641
DTXCID7099391
Ethanimidamide, N,N'-bis(4-chlorophenyl)-(9CI)
22365-62-4
NSC-194853
N,N'-bis(4-chlorophenyl)ethanimidamide
NSC194853
LV62ZNV3QY
SCHEMBL8529500
SCHEMBL8532271
N,N'-Di(p-chlorophenyl)acetamidine
Acetamidine,N'-bis(p-chlorophenyl)-
Ethanimidamide,N'-bis(4-chlorophenyl)-
Ethanimidamide, N,N'-bis(4-chlorophenyl)-, (E)-
141417-92-7