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N,N'-bis(p-tolyl)oxamide

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Identification
Molecular formula
C16H16N2O2
CAS number
33214-17-2
IUPAC name
N,N'-bis(p-tolyl)oxamide
State
State

At room temperature, N,N'-bis(p-tolyl)oxamide is in a solid state. It is not hygroscopic and maintains its structural integrity in typical room conditions.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.00
Boiling point (Celsius)
352.00
Boiling point (Kelvin)
625.00
General information
Molecular weight
268.32g/mol
Molar mass
268.3210g/mol
Density
1.2430g/cm3
Appearence

N,N'-bis(p-tolyl)oxamide appears as a crystalline solid with a light color, typically white or off-white. It tends to have a distinct crystalline structure.

Comment on solubility

Solubility of N,N'-bis(p-tolyl)oxamide

N,N'-bis(p-tolyl)oxamide is known for its intriguing solubility characteristics, which can be influenced by several factors. It typically exhibits moderate solubility in organic solvents, while its solubility in water is quite limited due to the non-polar nature of the tolyl groups attached to the oxamide functional groups. Here are some key points regarding its solubility:

  • Solvents: The compound is more soluble in organic solvents such as methanol, ethanol, and chloroform.
  • Temperature Dependence: Increased temperature often enhances its solubility in these organic solvents, making it easier to dissolve.
  • Hydrophobic Interactions: The bulky p-tolyl groups contribute to hydrophobic interactions, limiting aqueous solubility.

In summary, N,N'-bis(p-tolyl)oxamide exhibits moderate solubility in organic environments, while its solubility in polar solvents like water remains minimal. This aspect is important for its applications and behavior in various chemical processes.

Interesting facts

Interesting Facts about N,N'-bis(p-tolyl)oxamide

N,N'-bis(p-tolyl)oxamide is a fascinating compound that has attracted attention due to its unique chemical structure and potential applications in various fields. Here are some compelling insights about this intriguing oxamide:

  • Versatile Applications: This compound is known for its use in applications such as analytical chemistry and materials science, where it serves as a ligand in coordination chemistry.
  • Coordination Chemistry: N,N'-bis(p-tolyl)oxamide can form stable complexes with various metals, making it valuable in the synthesis of metal-organic frameworks and other supramolecular structures.
  • Research Interest: Researchers are particularly interested in its properties for catalysis and organometallic chemistry, where its dual amide functionality allows for diverse bonding scenarios with different metal ions.
  • Biological Significance: Some studies have suggested that derivatives of N,N'-bis(p-tolyl)oxamide may exhibit biological activity, making it a candidate for further exploration in drug development.
  • Synthesis: The synthesis of N,N'-bis(p-tolyl)oxamide typically involves the reaction of p-toluidine with various carbonyl compounds, showcasing an interesting method of creating complex organic molecules.

In summary, N,N'-bis(p-tolyl)oxamide is more than just a compound; it represents a bridge between organic chemistry and its practical applications in industry and research. With ongoing studies, it holds the promise of unlocking new avenues in material science and beyond!

Synonyms
p-Oxalotoluidide
N,N'-Di-p-tolyloxamide
NSC 401961
VXW61IZ0NZ
Ethanediamide, N,N'-bis(4-methylphenyl)-
OXAMIDE, N,N'-DI-p-TOLYL-
N,N'-Bis(4-tolyl)oxamide
BRN 2136359
N1,N2-Bis(4-methylphenyl)ethanediamide
UNII-VXW61IZ0NZ
NSC-401961
DTXSID10186622
3-12-00-02072 (Beilstein Handbook Reference)
ETHANEDIAMIDE, N1,N2-BIS(4-METHYLPHENYL)-
DTXCID50109113
Ethanediamide, N,N'-bis(4-methylphenyl)-(9CI)
3299-61-4
N,N'-bis(4-methylphenyl)oxamide
N1,N2-Di-p-tolyloxalamide
NSC401961
di-(p-tolyl)oxamide
Oxamide,N'-di-p-tolyl-
N,N'-bis(p-tolyl)oxamide
N,N'-bis(p-tolyl)-oxamide
Ethanediamide, N,N'-bis(4-methylphenyl)- (9CI)
SCHEMBL6850999
N-(4-Methylphenyl)-N'-(4-methylphenyl)ethane-1,2-diamide
STK150974
AKOS001023218
N,N'-bis(4-methylphenyl)ethanediamide
Ethanediamide,N'-bis(4-methylphenyl)-
CS-0362446
Z56755346