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N,N-Dibenzylphenethylamine

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Identification
Molecular formula
C22H21N
CAS number
535-47-5
IUPAC name
N,N-dibenzyl-1-phenyl-methanamine
State
State

At room temperature, N,N-Dibenzylphenethylamine is typically in a solid state but can be prepared and stored as a liquid through stabilization and containment at specific conditions.

Melting point (Celsius)
73.00
Melting point (Kelvin)
346.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
286.41g/mol
Molar mass
286.4110g/mol
Density
1.0650g/cm3
Appearence

N,N-Dibenzylphenethylamine typically appears as a clear to pale yellow liquid. As it is a synthetic compound mainly used in research, its physical form can vary depending on preparation methods and purity.

Comment on solubility

Solubility of N,N-dibenzyl-1-phenyl-methanamine

N,N-dibenzyl-1-phenyl-methanamine, with its complex structure, exhibits interesting solubility characteristics. Understanding its solubility is crucial for various applications in organic chemistry and pharmaceuticals. Here are some key points regarding its solubility:

  • Solvent Type: This compound is generally soluble in organic solvents such as ethanol, methanol, and chloroform, owing to its non-polar benzyl groups which interact well with non-polar solvents.
  • Water Solubility: Conversely, N,N-dibenzyl-1-phenyl-methanamine has limited solubility in water. This is primarily due to its hydrophobic characteristics, which hinder interaction with water molecules.
  • Temperature Influence: Increasing the temperature typically enhances the solubility of this compound in organic solvents, making it easier to manipulate in laboratory settings.
  • pH Sensitivity: The solubility may also be affected by the pH of the solution, since amines can exist in protonated forms that may enhance solubility in polar solvents.

In summary, while N,N-dibenzyl-1-phenyl-methanamine shows a tendency to dissolve in organic solvents, its limited water solubility may pose challenges for specific applications. Proper solvent selection can make all the difference in achieving the desired outcomes in practical scenarios.

Interesting facts

Interesting Facts about N,N-Dibenzyl-1-phenyl-methanamine

N,N-Dibenzyl-1-phenyl-methanamine is a fascinating compound that belongs to the class of secondary amines. It has garnered attention in the fields of organic chemistry and medicinal chemistry due to its unique structural attributes and potential applications.

Chemical Structure and Properties

The compound consists of a central methanamine group bonded to two benzyl groups and a phenyl group, creating an intriguing aromatic system. Some notable aspects include:

  • Aromatic Stability: The incorporation of multiple aromatic rings contributes to the compound's stability and potential reactivity.
  • Electronic Properties: The electron-donating nature of the benzyl and phenyl groups can influence the compound's reactivity, making it interesting for various chemical transformations.

Applications and Uses

N,N-Dibenzyl-1-phenyl-methanamine can be explored for several practical applications:

  • Pharmaceutical Development: Its structure allows for the design of novel compounds that may exhibit biological activity, particularly in drug discovery and development.
  • Organic Synthesis: It serves as a valuable intermediate for synthesizing other organic compounds, showcasing its versatility in chemical reactions.

Research Significance

This compound is a subject of ongoing research, particularly in:

  • Structure-Activity Relationship (SAR) Studies: By modifying its structure, researchers aim to enhance its biological properties.
  • Exploring Catalytic Properties: Investigations into its potential as a catalyst in certain reactions are also prevalent, aiming to improve reaction efficiencies.

In summary, N,N-dibenzyl-1-phenyl-methanamine is a compound rich in both structural complexity and potential for diverse applications, making it a captivating subject for chemists. Its ongoing research is likely to unveil even more exciting insights into its properties and functionalities.

Synonyms
Tribenzylamine
Benzenemethanamine, N,N-bis(phenylmethyl)-
N,N-dibenzyl-1-phenylmethanamine
n,n,n-tribenzylamine
UNII-HZ10O1931J
N,N-Bis(phenylmethyl)benzenemethanamine
DTXSID5047031
(N,N-Dibenzylaminomethyl)benzene
HZ10O1931J
EINECS 210-638-3
AI3-01809
DTXCID3027031
Benzenemethanamine, N,Nbis(phenylmethyl)
210-638-3
mxhtzqsktccmfg-uhfffaoysa-n
620-40-6
MFCD00004773
tribenzyl-amine
N,N-dibenzyl-1-phenyl-methanamine
Tribenzylamine, >=99%
SCHEMBL134524
N,N-Dibenzyl(phenyl)methanamine
CHEMBL3184803
N,N-Dibenzyl(phenyl)methanamine #
Tribenzylamine, >=99.0% (NT)
Tox21_302339
STL453637
AKOS003273171
NCGC00256253-01
AS-11949
CAS-620-40-6
SY049334
NS00010857
T0341
Q4462936
F0001-1653