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N,N-Dibutyl-2-fluoroacetamide

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Identification
Molecular formula
C10H20FNO
CAS number
21118-32-3
IUPAC name
N,N-dibutyl-2-fluoro-acetamide
State
State

At room temperature, N,N-Dibutyl-2-fluoroacetamide exists as a liquid. It is not volatile under standard conditions and does not easily transition between states.

Melting point (Celsius)
-45.00
Melting point (Kelvin)
228.15
Boiling point (Celsius)
253.00
Boiling point (Kelvin)
526.15
General information
Molecular weight
205.28g/mol
Molar mass
205.2820g/mol
Density
0.9510g/cm3
Appearence

N,N-Dibutyl-2-fluoroacetamide is typically a transparent, colorless to pale yellow liquid with a slight chemical odor. The liquid is consistent and homogeneous in nature.

Comment on solubility

Solubility of N,N-dibutyl-2-fluoro-acetamide

N,N-dibutyl-2-fluoro-acetamide, commonly known in the scientific community for its distinctive structure, displays intriguing solubility properties that are vital for various applications. Understanding its solubility can provide insights into its behavior in different environments:

  • Solvent Compatibility: This compound tends to be soluble in a range of organic solvents, particularly those with moderate polarity. It shows good solubility in polar aprotic solvents such as dimethyl sulfoxide (DMSO) and acetonitrile.
  • Water Solubility: N,N-dibutyl-2-fluoro-acetamide has limited solubility in water. This is primarily due to the hydrophobic butyl groups, which reduce its overall affinity for water.
  • Influencing Factors: Factors such as temperature and the presence of other solutes can significantly affect its solubility. For instance, increasing temperature generally enhances solubility in organic solvents.

As with many organic compounds, the solubility of N,N-dibutyl-2-fluoro-acetamide underscores the importance of molecular structure in determining how well it can dissolve in various media. Knowing these solubility characteristics is essential for chemists working with this compound in practical applications and synthesis.

Interesting facts

Interesting Facts about N,N-dibutyl-2-fluoro-acetamide

N,N-dibutyl-2-fluoro-acetamide is a fascinating compound with intriguing properties and applications. Here are some noteworthy facts:

  • Structure and Composition: This compound contains two butyl groups attached to the nitrogen atom, which contributes to its unique chemical behavior and lipophilicity.
  • Fluorine Influence: The presence of a fluorine atom significantly alters the molecule's properties, often enhancing its biological activity and making it more stable against degradation.
  • Potential Use in Synthesis: It is commonly used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals, creating compounds that exhibit biological activities.
  • Solvating Agent: N,N-dibutyl-2-fluoro-acetamide can function as a solvating agent in various chemical reactions, playing a pivotal role in improving reaction conditions and yields.
  • Research Applications: Ongoing research explores its efficacy in medicinal chemistry, particularly in creating targeted drug delivery systems.

The study of N,N-dibutyl-2-fluoro-acetamide opens up new avenues in the fields of organic chemistry and pharmaceutical development. As scientists continue to unravel its potential, this compound exemplifies the importance of modifying chemical structures to achieve desirable properties.

As Albert Einstein once said, "The important thing is not to stop questioning." With compounds like N,N-dibutyl-2-fluoro-acetamide, the questions are abundant, and the discoveries continue to unfold!

Synonyms
N,N-Dibutyl-2-fluoroacetamide
ACETAMIDE, N,N-DIBUTYL-2-FLUORO-
BRN 1768011
325-85-9
DTXSID90186226
4-04-00-00568 (Beilstein Handbook Reference)
DTXCID00108717