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N,N-dibutyl-4-chlorobenzenesulfonamide

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Identification
Molecular formula
C14H22ClNO2S
CAS number
1600-80-6
IUPAC name
N,N-dibutyl-4-chloro-benzenesulfonamide
State
State

At room temperature, N,N-dibutyl-4-chlorobenzenesulfonamide is in a solid state. It maintains its structural integrity as a crystalline solid under standard conditions.

Melting point (Celsius)
42.00
Melting point (Kelvin)
315.15
Boiling point (Celsius)
399.60
Boiling point (Kelvin)
672.75
General information
Molecular weight
321.87g/mol
Molar mass
321.8650g/mol
Density
1.1554g/cm3
Appearence

N,N-dibutyl-4-chlorobenzenesulfonamide appears as a white to pale yellow crystalline solid. It exhibits a typically consistent and homogeneous appearance without significant variation in color or texture.

Comment on solubility

Solubility of N,N-Dibutyl-4-chloro-benzenesulfonamide

N,N-Dibutyl-4-chloro-benzenesulfonamide is a complex organic compound whose solubility can be influenced by various factors, notably its molecular structure and polarity. Here are some key points regarding its solubility:

  • Polarity: The presence of the sulfonamide group and the chlorobenzene ring typically contributes to a significant dipole moment, suggesting that the compound may exhibit varying solubility in different solvents.
  • Hydrophobic Properties: Given the two butyl groups, the molecule is likely to have hydrophobic characteristics, making it more soluble in organic solvents.
  • Solvent Compatibility: It is expected to exhibit moderate solubility in non-polar and slightly polar solvents, such as:
    • Chloroform
    • Ethyl acetate
    • Hexane
  • Limited Solubility in Water: Due to its hydrophobic nature, the solubility in water is likely to be quite low. This limited solubility can pose challenges in applications requiring aqueous environments.

In summary, while N,N-dibutyl-4-chloro-benzenesulfonamide demonstrates reasonable solubility in organic solvents, it exhibits poor solubility in water, highlighting the importance of selecting appropriate solvents for practical applications.

Interesting facts

Interesting Facts about N,N-dibutyl-4-chloro-benzenesulfonamide

N,N-dibutyl-4-chloro-benzenesulfonamide is a fascinating compound with a variety of applications and attributes that intrigue chemists and researchers alike.

Key Attributes:

  • Chemical Structure: This compound features a benzenesulfonamide backbone, which is a key structure in many pharmaceutical molecules.
  • Sulfonamide Derivative: As a sulfonamide, it shares a rich history with antibiotics and has historical significance in the development of medicinal chemistry.
  • Chlorination: The presence of chlorine at the para position enhances both its biological activity and stability, making it a noteworthy subject of study.

Applications and Relevance:

This versatile compound is often explored in various fields, including:

  • Pharmaceutical Development: It is a candidate for drug synthesis due to its sulfonamide functionality, pointing to potential therapeutic uses.
  • Pesticide Formulations: Its structural properties make it beneficial in developing agrichemicals.
  • Research Tool: N,N-dibutyl-4-chloro-benzenesulfonamide is utilized in biochemical assays to investigate enzyme activity and inhibition.

Furthermore, researchers studying this compound often quote the words of famous chemists noting its significance: "The beauty of chemistry lies in the diverse roles that simple molecules can play in the intricate dance of life."
This highlights how even a single compound can have multiple implications across different scientific domains.

Safety and Handling:

As with many chemical compounds, it is essential to observe proper safety protocols when handling N,N-dibutyl-4-chloro-benzenesulfonamide, as it may exhibit toxicity in certain conditions. Always refer to safety data sheets (SDS) and follow laboratory guidelines.

In summary, N,N-dibutyl-4-chloro-benzenesulfonamide is more than just a chemical structure; it represents a crossroads of medicinal chemistry, environmental science, and research innovation. Its dual potential as both a pharmaceutical agent and a research tool makes it particularly compelling in contemporary science.

Synonyms
N,N-Dibutyl-4-chlorobenzenesulfonamide
DDT warf antiresistant
N,N-Dibutyl-p-chlorobenzenesulfonamide
127-59-3
Warf antiresistant
N,N-Di-n-butyl-p-chlorobenzenesulfonamide
Benzenesulfonamide, N,N-dibutyl-4-chloro-
BENZENESULFONAMIDE, N,N-DIBUTYL-p-CHLORO-
AR 10
JKK0AO0V6M
Benzenesulfonamide, p-chloro-N,N-dibutyl-
Warf Antiresistant for Ddt
DTXSID3042186
AR-10
Antiresistant
Pramax
Caswell No. 291
Warf DDT anti-resistant
UNII-JKK0AO0V6M
EPA Pesticide Chemical Code 017201
BRN 3060323
AI3-26459
CBMicro_006700
RefChem:1090408
SCHEMBL8602183
DTXCID1022186
CLVOYFRAZKMSPF-UHFFFAOYSA-N
SMSF0005580
STK060929
AKOS003269576
dibutyl[(4-chlorophenyl)sulfonyl]amine
CB09021
N,N-dibutyl-4-chlorobenzenesul-fonamide
N,N-Dibutyl-4-chlorobenzenesulfonamide #
BIM-0006516.P001
NS00120732
ST50692394
DIBUTYL-P-CHLOROBENZENESULFONAMIDE, N,N-
AO-854/11634512
N,N-DI-N-BUTYL-P-CHLOROBENZENESULPHONAMIDE
N,N-DIBUTYL-4-CHLOROBENZENE-1-SULFONAMIDE
Q27281551