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Diethyltryptamine

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Identification
Molecular formula
C14H20N2
CAS number
61-50-7
IUPAC name
N,N-diethyl-2-(1H-indol-3-yl)ethanamine
State
State

At room temperature, diethyltryptamine is typically found in a liquid state. It might also exist as a colorless oil that can be converted into salt forms for solid-state applications.

Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
292.00
Boiling point (Kelvin)
565.15
General information
Molecular weight
218.34g/mol
Molar mass
218.3360g/mol
Density
1.1180g/cm3
Appearence

Diethyltryptamine (DET) typically appears as a colorless oil or liquid at room temperature. It can sometimes be found as crystalline solids if specially prepared. This compound is known for its transparency and potential to crystallize under specific conditions.

Comment on solubility

Solubility of N,N-Diethyl-2-(1H-Indol-3-yl)ethanamine

N,N-Diethyl-2-(1H-indol-3-yl)ethanamine, with the chemical formula C14H20N2, exhibits specific solubility characteristics that are noteworthy.

General Solubility Behavior

This compound primarily demonstrates moderate solubility in various organic solvents, often influenced by the presence of the indole structure which contributes to its non-polar character. The following points summarize its solubility:

  • Solvent Compatibility: Commonly soluble in non-polar organic solvents such as ethanol and chloroform.
  • Water Solubility: Limited water solubility is observed, likely due to its hydrophobic indole ring, which hinders interactions with water molecules.
  • Temperature Dependence: Solubility may increase with temperature, a typical property of many organic compounds.

Factors Affecting Solubility

Several factors can influence the solubility of N,N-diethyl-2-(1H-indol-3-yl)ethanamine, including:

  • pH Levels: The ionization of the amine group can vary with pH, leading to changes in overall solubility.
  • Presence of Other Solutes: The interactions between this compound and other solutes in a solution can impact its solubility profile.

This compound's solubility characteristics can make it a useful candidate in various applications, particularly in **pharmaceutical** formulations where solubility plays a critical role in bioavailability.

Interesting facts

Interesting Facts about N,N-Diethyl-2-(1H-Indol-3-yl)ethanamine

N,N-Diethyl-2-(1H-indol-3-yl)ethanamine, commonly known as a derivative of indole, is a fascinating compound that has garnered attention in both the fields of organic chemistry and pharmacology. Here are some noteworthy facts about this intriguing molecule:

  • Structure and Function: This compound features an indole moiety, which is a bicyclic structure that comprises a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. Indole derivatives are important in medicinal chemistry due to their structural similarity with various neurotransmitters.
  • Biological Activity: Compounds in this class are often studied for their potential pharmacological effects. Research shows that they may exhibit psychoactive properties, contributing to their investigation in the context of neurological disorders and mental health treatments.
  • Applications in Research: Scientists are exploring N,N-diethyl-2-(1H-indol-3-yl)ethanamine for its potential as a tool in investigating the serotonin receptors. These receptors play a critical role in regulating mood, anxiety, and cognitive functions.
  • Synthetic Routes: The synthesis of this compound can involve a series of chemical reactions, including alkylation and amination. The methods for its synthesis often emphasize the need for precision to achieve high purity and desired yields.
  • Historical Significance: Indole derivatives have played a significant role in the discovery of various therapeutic agents, including antidepressants and anxiolytics, marking a historical connection between organic chemistry and modern medicine.

In summary, N,N-diethyl-2-(1H-indol-3-yl)ethanamine stands out not only for its unique structure and biological relevance but also for its potential implications in the broader fields of pharmacology and neuroscience. As research continues to unveil new properties and applications, this compound remains a subject of great interest for chemists and medical researchers alike.

Synonyms
N,N-Diethyltryptamine
Diethyltryptamine
61-51-8
3-(2-Diethylaminoethyl)indole
N,N-Diethyl-2-(1H-indol-3-yl)ethanamine
1H-Indole-3-ethanamine, N,N-diethyl-
INDOLE, 3-(2-(DIETHYLAMINO)ETHYL)-
BRN 0153320
916E8V4S2V
CHEMBL142936
D.E.T.
DTXSID9052763
5-22-10-00050 (Beilstein Handbook Reference)
3-(2-(DIETHYLAMINO)ETHYL)INDOLE
diethyl(2-(1H-indol-3-yl)ethyl)amine
diethyl[2-(1H-indol-3-yl)ethyl]amine
UNII-916E8V4S2V
DEA No. 7434
NN-Diethyltryptamine
Oprea1_105894
SCHEMBL517713
DTXCID7031373
CHEBI:184081
LSSUMOWDTKZHHT-UHFFFAOYSA-N
BDBM50094676
STK368075
AKOS005444987
DB01460
Diethyl-[2-(1H-indol-3-yl)-ethyl]-amine
NS00098694
1H-Indole-3-ethanamine, N,N-diethyl-(9CI)
N,N-Diethyl-2-(1H-indol-3-yl)ethanamine #
C22726
Q2617768
102-975-9