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No scientific common name

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Identification
Molecular formula
C23H30ClNO
CAS number
448906-42-1
IUPAC name
N,N-diethyl-2-[2-(2-methyl-5-phenyl-pyrrol-1-yl)phenoxy]ethanamine;hydrochloride
State
State

At room temperature, this compound is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
296.00
Boiling point (Kelvin)
569.15
General information
Molecular weight
402.96g/mol
Molar mass
402.9580g/mol
Density
1.3262g/cm3
Appearence

N,N-diethyl-2-[2-(2-methyl-5-phenyl-pyrrol-1-yl)phenoxy]ethanamine;hydrochloride appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N,N-Diethyl-2-[2-(2-Methyl-5-Phenyl-Pyrrol-1-Yl)Phenoxy]ethanamine; Hydrochloride

The solubility of N,N-diethyl-2-[2-(2-methyl-5-phenyl-pyrrol-1-yl)phenoxy]ethanamine; hydrochloride is a crucial factor that influences its applications in various fields, particularly in pharmaceuticals. Here are some key points to consider:

  • Presence of Hydrochloride: As a hydrochloride salt, this compound is often more soluble in water compared to its free base form. This characteristic is beneficial, as solubility in aqueous solutions is vital for drug formulation and bioavailability.
  • Influencing Factors: The solubility can be significantly affected by factors such as pH, temperature, and the presence of other ions or solvents in the solution:
    • pH Levels: The solubility tends to increase in acidic conditions due to the protonation of the amine functional groups.
    • Temperature: Higher temperatures usually enhance the solubility of many compounds; however, this can vary based on the specific interactions of the compound with solvents.
  • Polar vs. Non-Polar Solvents: For effective dissolution, this compound is more likely to be soluble in polar solvents due to its ionic character from the hydrochloride formation.

In summary, the solubility of N,N-diethyl-2-[2-(2-methyl-5-phenyl-pyrrol-1-yl)phenoxy]ethanamine; hydrochloride is generally high in aqueous solutions, primarily due to its salt form and polar characteristics. Understanding and optimizing its solubility is essential for maximizing its efficacy in practical applications.

Interesting facts

N,N-Diethyl-2-[2-(2-methyl-5-phenyl-pyrrol-1-yl)phenoxy]ethanamine; hydrochloride

N,N-Diethyl-2-[2-(2-methyl-5-phenyl-pyrrol-1-yl)phenoxy]ethanamine; hydrochloride is a fascinating compound that has garnered attention in various fields of research, including medicinal chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Pharmacological Potential: This compound is of interest for its potential use in treating neurological disorders. It may act as a modulator of neurotransmitter systems, which can be crucial in managing conditions such as depression or anxiety.
  • Pyrrolidine Backbone: The presence of the pyrrolidine ring in its structure contributes to its biological activity. Rings such as these are often found in many natural alkaloids and pharmaceutical agents, highlighting the compound's potential pharmacological significance.
  • Structure-Activity Relationship (SAR): Researchers are focused on studying the structure-activity relationship of this compound. Understanding how modifications to its structure impact its biological activity can lead to the development of more effective therapeutic agents.
  • Experimental Applications: In laboratory settings, this compound can be utilized in various assays to explore its binding affinities and interactions with specific biological targets, making it a useful tool for neuroscientific research.
  • Synthesis Challenges: The synthesis of this compound can be quite challenging due to the intricate structure. Chemists often work to optimize synthetic routes to enhance yield and purity, which remains a critical aspect of compound development.

In summary, N,N-diethyl-2-[2-(2-methyl-5-phenyl-pyrrol-1-yl)phenoxy]ethanamine; hydrochloride presents a promising area for exploration in both medicinal chemistry and pharmacology. Its unique structural features and potential therapeutic applications make it a compound worth studying in greater depth.

Synonyms
Leioplegil
4N4RH67VMX
LEIOPYROLE HYDROCHLORIDE
NSC-83995
DV 714 HYDROCHLORIDE
DV-714 HYDROCHLORIDE
Leiopyrrole hydrochloride
14435-78-0
Ethanamine, N,N-diethyl-2-(2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)phenoxy)-, monohydrochloride
Pyrrole, 1-(o-(2-(diethylamino)ethoxy)phenyl)-2-methyl-5-phenyl-, monohydrochloride
Leiopyrrole HCl
NSC 83995
UNII-4N4RH67VMX
1-(o-(2-(Diethylamino)ethoxy)phenyl)-2-methyl-5-phenylpyrrole hydrochloride
Chlorhydrate de (beta-diethylaminoethoxy-2-phenyl)-1 phenyl-2 methyl-5 pyrrole [French]
SCHEMBL317830
DTXSID10162683
NSC83995
LEIOPYROLE HYDROCHLORIDE [MI]
Chlorhydrate de (beta-diethylaminoethoxy-2-phenyl)-1 phenyl-2 methyl-5 pyrrole
1-(2-(2-DIETHYLAMINOETHOXY)PHENYL)-2-METHYL-5-PHENYLPYRROLE HYDROCHLORIDE
PYRROLE, 1-(O-(2-(DIETHYLAMINO)ETHOXY)PHENYL)-2-METHYL-5-PHENYL-, HYDROCHLORIDE
ETHANAMINE, N,N-DIETHYL-2-(2-(2-METHYL-5-PHENYL-1H-PYRROL-1-YL)PHENOXY)-, HYDROCHLORIDE
ETHANAMINE, N,N-DIETHYL-2-(2-(2-METHYL-5-PHENYL-1H-PYRROL-1-YL)PHENOXY)-, HYDROCHLORIDE (1:1)